Analysis of risk factors of chronic obstructive pulmonary disease respiratory failure complicated with pulmonary infection
Objective To explore the risk factors of chronic obstructive pulmonary disease(COPD)respiratory failure compli-cated with pulmonary infection,and to explore the effect of comprehensive intervention mode on pulmonary function of pa-tients.Methods By simple sampling method,87 patients with COPD respiratory failure who were treated in our hospital from Jan.2021 to Jan.2022 were selected as the research objects,and divided into infection group and non-infection group ac-cording to whether they were complicated with pulmonary infection.The gender,age and underlying diseases of the patients were collected to explore the risk factors of COPD respiratory failure complicated with pulmonary infection and the distribution characteristics of infectious pathogens,and corresponding preventive measures were formulated according to the risk factors.Results Toatlly 51 patients(58.62％)with pulmonary infection and 36 patients(41.38％)without pulmonary infection in 87 COPD patients with respiratory failure.Logistic regression analysis showed that age ≥65,use of mechanical ventilation,hypoproteinemia,history of diabetes,long-term ICU stay,long-term use of antibiotics,long-term use of glucocorticoids were independent risk factors for pulmonary infection in COPD patients with respiratory failure(P＜0.05).A total of 81 pathogens were detected in patients with pulmonary infection,including 17 fungi,36 gram-negative strains and 28 gram-positive strains.Conclusion COPD patients with respiratory failure by pulmonary infection is related to age,mechanical ven-tilation,hypoalbuminemia,history of diabetes mellitus,length of ICU stay and antibiotics and the use of glucocorticoid.The risk factors should be effectively monitoring and intervention,to further reduce the risk of pulmonary infection in COPD patients with respiratory failure and improve the prognosis of patients through pathogen isolation and protection.
Chronic obstructive pulmonary diseaseRespiratory failureLung infectionRisk factorsComprehensive inter-vention modelLung function
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万方数据
