Correlation between quantitative parameters of DCE-MRI and postoperative recurrence,metastasis and clinicopathological characteristics of breast cancer patients
Objective To explore the correlation between quantitative parameters of dynamic contrast-enhanced mag-netic resonance imaging(DCE-MRI)and postoperative recurrence,metastasis and clinicopathological characteristics of breast cancer patients.Methods A total of 120 patients with breast cancer who received modified radical mastectomy in our hospital from Jan 2018 to Dec 2021 were selected as research subjects.Clinical medical records of patients were col-lected.The tumor tissue of breast cancer patients was scanned by DCE-MRI.The correlation between postoperative clinicopathological features of patients with breast cancer and radiomic features of DCE-MRI was analyzed.Results The values of Ktrans and Kep were significantly different in tumor size,histological grade,lymph node metasta-sis,ER expression and PR expression(P＜0.05).There were no significant differences in Ve values between different tumor sizes,lymph node metastasis,ER expression and PR expression except histological grade(P＜0.05).Ktrans and Kep values in patients with recurrence and metastasis were higher than those in patients without recurrence and metastasis(P＜0.05),but there was no significant difference in Ve values between the two groups(P＞0.05).Tumor size,his-tological grade,lymph node metastasis,ER expression and PR expression were correlated with Ktrans and Kep(P＜0.05),while Ve was correlated with histological grade(P＜0.05),but not with tumor size,lymph node metasta-sis,ER expression and PR expression(P＞0.05).Conclusion DCE-MRI imaging parameters Ktrans,Kep and Ve are correlated with clinicopathological features and postoperative recurrence and metastasis of breast cancer patients.DCE-MRI can help to evaluate the condition and postoperative metastasis and recurrence of breast cancer patients.
Breast cancerDCE-MRIImaging parametersPathological featuresCorrelation
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