Influence of blood routine changes on periprosthetic joint infection in patients with knee osteoarthritis before and after knee replacement
Objective To observe the changes of blood routine in patients with knee osteoarthritis before and after knee re-placement,and analyze the influence of blood routine changes on periprosthetic joint infection,so as to provide reference for the prevention and treatment of periprosthetic joint infection in patients with knee osteoarthritis.Methods A prospec-tive study was conducted on 91 patients with knee osteoarthritis who underwent knee replacement in Anyang Iron and Steel Group Co.,Ltd.Employee General Hospital from June 2020 to June 2021.The levels of white blood cell count(WBC),platelet count(PLT)and hemoglobin(HGB)were measured before operation,3 days after operation and 1 month after operation.The incidence of periprosthetic joint infection was observed 1 month after operation.The relationship between periprosthetic joint infection and the levels of WBC,PLT and HGB before and after operation was compared.Results Af-ter knee replacement,3 patients had periprosthetic joint infection,the infection rate was 3.30％.The levels of WBC,PLT and HGB in patients with knee osteoarthritis at 3 days and 1 month after operation were higher than those before operation,with a statistical significant difference(P＜0.05).The levels of WBC,PLT and HGB in patients with periprosthetic joint infection before operation,at 3 days after operation and at 1 month after operation were higher than those of patients with-out periprosthetic joint infection,with a statistical significant difference(P＜0.05).Conclusion Patients with knee os-teoarthritis have abnormal blood routine before operation and the blood routine value after operation is abnormally higher than that before operation,so the risk of periprosthetic joint infection is higher.
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