Analysis of prognostic factors affecting ECMO transport in pediatric patients
Objective To explore the prognostic factors of extracorporeal membrane oxygenation(ECMO)transport in children.Methods A retrospective statistical analysis was conducted on the clinical data of 57 pediatric patients who un-derwent extracorporeal membrane transport by the Children's ECMO team of Henan Provincial Peoples Hospital from Janu-ary 1,2018 to March 31,2023 at the referral institution.Results The ECMO team transferred 57 children from 39 refer-ral facilities,all by land ambulance,with an average transport distance of(170.2±11.8)km.There were 4 neonates(7.0％)and 53 non-neonates(93.0％).Veno-venous mode was used in 3 cases(5.3％),and Veno-arterial mode was used in 54 cases(94.7％).Thirty-one patients died,24 survived,and 2 patients were transferred to Fuwei Hospital for cardiovascular surgery due to abnormal coronary origin and pulmonary arteriovenous stenosis,respectively.There were significant differences in PCIS score,erythrocyte,platelet,hemoglobin,alanine transaminase,prothrombin time,partially activated thrombin time,D-dimer and creatinine between survival group and death group(P＜0.05).There were no sta-tistically significant differences in age,gender,whether patients were admitted on weekdays,whether patients were admit-ted at night,transport distance,grade of referral hospital(whether it was a third-class A hospital),whether there was multiple organ failure,cardiac arrest before ECMO,mechanical ventilation,application of vasoactive drugs,and ECMO support mode(P＞0.05).logistic regression analysis was performed for the different factors,and the results showed that the lower the PCIS score and the longer the prothrombin time,the higher the risk of death(OR=0.83,95％CI 0.719-0.958,P＜0.05;OR=1.102,95％CI 1.003-1.21,P＜0.05).Conclusion PCIS score and prothrombin time at admission are factors that affect the prognosis of children with ECMO transport.
Extracorporeal membrane oxygenationTransport of childrenPCIS scoreProthrombin time
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