Risk factors of pneumonia in head and neck cancer patients with radiotherapy
Objective To investigate the influencing factors of periradiotherapy pneumonia in patients with head and neck tumor,and to evaluate the predictive effect of influencing factors on acute pneumonia.Methods A total of 187 head and neck tumor patients treated with radiotherapy in the First Affiliated Hospital of Xinxiang Medical College were selected from July 2018 to Dec.2021.The incidence of periradiotherapy pneumonia was analyzed,and the patients were divided into the occurrence group and the non-occurrence group according to whether pneumonia occurred.Twelve patients who developed pneumonia after radiotherapy were included in the developing group and 175 patients who did not develop pneumonia were included in the non-developing group.The variables with statistical difference were selected through univariate analysis of baseline data,and the influencing factors of periradiotherapy pneumonia in patients with head and neck tumors were analyzed by multivariate logistic regression analysis.ROC curve was used to evaluate the predictive effect of influencing factors on the incidence of acute pneumonia.Results Univariate analysis and logistic regression analysis showed that age ≥60 years and serum albumin level＜40g/L before treatment were the influencing factors of periradiotherapy pneumonia in patients with head and neck tumor(P＜0.05).ROC curve a-nalysis showed that the area under the curve for predicting the incidence of teratopneumonia by age was 0.709± 0.068.Conclusion Age ≥60 years and serum albumin level＜40 g/L before treatment are the influential factors for the occurrence of periradiotherapy pneumonia in patients with head and neck tumor(P＜0.05).Age was a good predictor of acute pneumonia.
Head and neck tumorRadiation therapyPneumoniaAge:Serum albumin
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