首页|胸腹主动脉瘤患者行腔内修复术对比血管置换术对炎性因子及生活质量的影响

胸腹主动脉瘤患者行腔内修复术对比血管置换术对炎性因子及生活质量的影响

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目的 探讨胸腹主动脉瘤(thoracoabdominal aortic aneurysm,TAA)患者采用腔内覆膜支架置入术对炎性因子及生活质量的影响。方法 选取2019年4月-2022年4月郑州大学第一附属医院收治的胸腹主动脉瘤患者96例,按手术方法分组,采用人造血管置换术治疗的48例作为对照组,采用腔内覆膜支架置入术治疗的48例作为观察组,比较两组患者的手术相关指标、炎性因子指标、并发症发生率及生存率、生活质量等指标。结果 观察组住院天数、术中出血量、手术及ICU观察时间分别为(14。37±3。28)d、(63。47±22。03)mL、(148。18± 33。99)min及(8。99±2。15)h,均少于对照组(P<0。05)。治疗前两组患者肿瘤坏死因子(TNF-α)、白介素-6(IL-6)及C反应蛋白(CRP)炎性因子水平比较无统计学意义(P>0。05),治疗后均降低,且观察组分别为(9。90±3。13)ng/L、(61。89±5。49)ng/L 及(4。27±0。99)mg/L,均低于对照组(P<0。05)。观察组并发症发生率6。25%,低于对照组的16。67%(P<0。05),随访1年后,观察组和对照组生存率比较无统计学意义(P>0。05)。治疗前2组SF-36五个项目评分比较无统计学意义(P>0。05),治疗后均提升,且观察组五个项目评分均高于对照组(P<0。05)。结论 腔内覆膜支架置入术对比血管置换术可明显改善TAA患者手术指标,降低炎性因子水平,促进康复,改善患者生活质量,可长期推广。
Effect of endovascular repair on inflammatory factors and SF-36 scores in patients with thoracoabdominal aortic aneurysm compared with vascular replacement
Objective This article mainly studied the effect of intraoperative blood loss and postoperative rehabilitation of patients with aneurysm aortic thoracoabdominal affected by stent endovascular implantation.Methods A total of 96 pa-tients with thoracic and abdominal aortic aneurysms admitted to the vascular surgery department of our hospital from April 2019 to April 2022 were selected and grouped according to surgical methods.48 patients treated with artificial vascular replacement for aneurysms were selected as the control group,and 48 patients treated with endovascular stent implanta-tion were selected as the observation group.The indexes related to surgery,inflammatory factors,complication rate,sur-vival rate and quality of life were compared between the two groups.Results The hospitalization days,operation time,intraoperative blood loss and ICU observation time in observation group were(14.37±3.28)d,(148.18±33.99)min,(63.47±22.03)mL and(8.99±2.15)h(P<0.05).There was no statistical significance in the levels of tumor necrosis factor(TNF-α),interleukin-6(IL-6)and C-reactive protein(CRP)in the two groups before treatment(P>0.05).The results of observation group were(9.90±3.13)ng/L,(61.89±5.49)ng/L and(4.27±0.99)mg/L,respectively,which were lower than group control(P<0.05).The group observation of complications incidence was 6.25%,lower than group control(16.67%)(P<0.05).After 1 year of follow-up,there was no significant difference in survival rate between the observation group and the control group(P>0.05).There was no significant difference in SF-36 scores between the two groups before treatment(P>0.05).and after treatment,the two groups was improved significantly the life of score quality,and the observation group was higher than control group(P<0.05).Conclusion Compared with vascular replacement,endovascular stent implantation can significantly improve the surgi-cal indicators of TAA patients,reduce the level of inflammatory factors,promote rehabilitation,improve the quality of life of patients,and can be extended in the long term.

Thoracoabdominal aortic aneurysmEndovascular prosthesisVascular replacementIntraoperative blood lossEndocaval coated stentSerum factor

葛琼、吴世勇、允清玲、马珂

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郑州大学第一附属医院血管外科,郑州 450052

胸腹主动脉瘤 腔内修复术 血管置换术 炎性因子 并发症发生率 生活质量

2024

医药论坛杂志
中华预防医学会,河南省医学情报研究所

医药论坛杂志

影响因子:0.47
ISSN:1672-3422
年,卷(期):2024.45(8)
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