Epidemic characteristics of hepatitis B among first-time blood donors in Zhengzhou from 2017 to 2022
Objective To investigate the prevalence of hepatitis B surface antigen serum markers among first-time blood donors in Zhengzhou,evaluate the prevention and control effect of hepatitis B,identify high-risk blood donors,and provide evidence for prevention and control strategies.Methods Before blood donation,hepatitis B surface antigen(HBAG)was initially screened by gold standard test strip method,and the results were recorded into the blood collection and supply statistical software.The data of blood donors in Zhengzhou from 2017 to 2022 were retrospectively collected,and the year,season,species,sex,age,education background,occupation and ethnicity were statistically analyzed by de-scriptive epidemiological methods.SPSS 19.0 statistical software was used for statistical analysis.Results From 2017 to 2022,there were 770775 first-time blood donors and 5348 hepatitis B surface antigen positive in Zhengzhou.The av-erage annual positive rate was 0.69％,and the annual positive rate was 0.96％,0.73％,0.65％,0.60％,0.57％,0.66％,and there was a decreasing trend year by year.The positive rate of hepatitis B was seasonal,and the first quarter(0.83％)and third quarter(0.81％)were higher than other quarters.Those who donated whole blood(0.69％)were lower than those who donated platelets(0.87％).The positive rate of males(0.85％)was higher than that of females(0.44％).The highest positive rate was 46-55 years old(1.15％),followed by 36-45 years old(1.00％)and 18-25 years old(0.42％).The positive rate increased with age.The positive rate of primary school education group was the highest(1.42％),followed by junior high school(1.11％),and the positive rate decreased with the increase of educational background.Farmers had the highest positive rate(1.25％),followed by workers(0.95％).The positive rate of Han nationality(0.69％)was lower than that of minority nationality(0.88％).There were statistically signifi-cant differences in the positive rate among the above groups(P＜0.01).Conclusion The infection rate of hepatitis B among blood donors in Zhengzhou was decreasing year by year.It was a low epidemic area,and the prevention and con-trol effect of hepatitis B was remarkable.The risk factors of hepatitis B infection in blood donors are related to age,gen-der,occupation and educational background,etc.Blood donors should be recruited from low-risk groups such as students,civil servants,doctors and college graduates to reduce the risk of hepatitis B infection through blood transfusion.
Zhengzhou CityBlood donorsHepatitis BHBsAgHepatitis B vaccine
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NSTL
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