首页|急性呼吸窘迫综合征合并症对治疗及预后的影响

急性呼吸窘迫综合征合并症对治疗及预后的影响

扫码查看
目的 探讨合并症对急性呼吸窘迫综合征(acute respiratory distress syndrome,ARDS)患者入院后治疗及生存状况的影响。方法 选取2020年1月—2022年4月在安阳市人民医院ICU内进行有创或无创机械通气治疗的ARDS患者247例。应用logisitic回归分析合并症数目和单一合并症对ARDS患者预后指标如院内死亡、ICU内死亡、应用生命维持装置的影响。结果 相较于无合并症患者,存在合并症患者接受无创(mechanical ventilation,MV)的时间更长,有创MV时间更短;慢性呼吸衰竭、充血性心力衰竭、慢性肾衰竭、慢性肝衰竭、免疫功能不全、糖尿病、合并症数目多是ARDS患者ICU死亡的危险因素(P<0。05);慢性呼吸衰竭、充血性心力衰竭、慢性肾衰竭、慢性肝衰竭、免疫功能不全、糖尿病、合并症数目多是ARDS患者院内死亡的危险因素(P<0。05);慢性呼吸衰竭、充血性心力衰竭、慢性肾衰竭、慢性肝衰竭、免疫功能不全、糖尿病、合并症数目是ARDS患者应用生命维持装置的危险因素(P<0。05)。结论 大多数ARDS患者存在明显的合并症,他们接受的治疗较少,预后较差。加强对这些患者的治疗必然是未来临床研究的重点。
Effects of complications on treatment and prognosis of acute respiratory distress syndrome
Objective To investigate the effect of complications on the treatment and survival of patients with acute respir-atory distress syndrome(ARDS)after admission.Methods Totally 247 ARDS patients who were treated with invasive or noninvasive mechanical ventilation in the ICU of Anyang Peoples Hospital in January 2020 and April 2022 were selected.Logistic regression was used to analyze the impact of the number of complications and single complication on the prognosis indicators of ARDS patients,such as hospital death,ICU death,and the use of life support devices.Results Compared with patients without complications,patients with complications have a longer time to receive noninvasive MV and a shorter time to receive invasive MV.Chronic respiratory failure,congestive heart failure,chronic renal failure,chronic liver fail-ure,immune insufficiency,diabetes,and a large number of complications were the risk factors for death in ICU of ARDS patients(P<0.05).Chronic respiratory failure,congestive heart failure,chronic renal failure,chronic liver failure,im-mune insufficiency,diabetes,and a large number of complications were the risk factors for hospital death of ARDS patients(P<0.05).Chronic respiratory failure,congestive heart failure,chronic renal failure,chronic liver failure,immune in-sufficiency,diabetes,and a large number of complications were the risk factors for the use of life support devices in pa-tients with ARDS(P<0.05).Conclusion Most patients with ARDS have obvious complications.They receive less treat-ment and have poor prognosis.Strengthening the treatment of these patients must be the focus of future clinical research.

ComplicationsAcute respiratory distress syndromePrognosis

陈景行、李娟、张洋、邢夏、李立敬、越丽霞

展开 >

安阳市人民医院呼吸与危重症医学科,河南安阳 455000

河南省人民医院公共事业发展部,郑州 450000

合并症 急性呼吸窘迫综合征 预后

河南省科技发展计划

212400410060

2024

医药论坛杂志
中华预防医学会,河南省医学情报研究所

医药论坛杂志

影响因子:0.47
ISSN:1672-3422
年,卷(期):2024.45(11)