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室性早搏对老年人群心力衰竭的影响

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目的 探讨动态心电图下室性早搏(premature ventricular complex,PVC)特征对老年人群心力衰竭(heart failure,HF)的影响。方法 2017年2月-2017年7月在郑州市第七人民医院行健康体检的老年人群817例作为研究对象。进行为期5年的随访,整理比较各项资料,并进行LVEF降低和HF发生的影响因素分析。结果 ①817例体检者5年随访结果,60例出现LVEF降低,LVEF下降率7。34%;39例体检者发生HF,HF发病率4。77%。LVEF下降和HF的发生率,均以PVC组明显为高,差异有统计学意义(P<0。05)。②回归结果显示:PVC的特征如偶联间期(CI)不等互差长及年龄,LVESD等是老年人群LVEF下降的危险因素(P<0。05,OR>1),而PVC的特征如频率、持续时间、起源位置未影响老年人群的LVEF下降(P>0。10)。③回归结果显示:PVC的特征如CI不等互差长及年龄、BMI、高血压、高脂血症、心肌梗死史、吸烟、血NT-proBNP等,均是老年人群HF发生的危险因素(P<0。05,OR>1),而PVC的特征如频率、持续时间、起源位置和老年人群的HF发生无密切关联(P>0。05)。结论 PVC频率、PVC持续时间、PVC起源位置对老年人群LVEF下降和发生HF事件无影响;PVC的偶联间期不等互差长与人群LVEF下降和发生HF事件相关。偶联间期不等是独立的危险因素。
Effect of ventricular premature beats on heart failure in elderly population
Objective To investigate the impact of the characteristics of PVC under dynamic electrocardiogram on HF in the elderly population.Methods Totally 817 elderly individuals who underwent health examinations in the Seventh Peo-ple's Hospital of Zhengzhou from February 2017 to July 2017 were selected as the study subjects.Conduct a 5-year fol-low-up,adjust and compare various data,and analyze the influencing factors of LVEF reduction and HF occurrence.Results ①According to the 5-year follow-up results of 817 physical examinees,60 cases showed a decrease in LVEF,with a decrease rate of 7.34%;39 physical examinees developed HF,and the incidence rate of HF was 4.77%.The incidence of LVEF decrease and HF were significantly higher in the PVC group,and the difference were statistically significant(P<0.05).② The regression results showed that the characteristics of PVC,such as CI inequal-ity,age,and LVESD,were risk factors for LVEF decline in the elderly population(P<0.05,OR>1),while the char-acteristics of PVC,such as frequency,duration,and origin location,did not affect LVEF decline in the elderly popula-tion(P>0.10).③The regression results showed that the characteristics of PVC,such as CI inequality,age,BMI,hy-pertension,hyperlipidemia,history of myocardial infarction,smoking,and blood NT-proBNP,were all risk factors for HF occurrence in the elderly population(P<0.05,OR>1),while the characteristics of PVC,such as frequency,du-ration,origin location,and HF occurrence in the elderly population were not closely related(P>0.05).Conclusion PVC frequency,PVC duration,and PVC origin location have no effect on the decrease of LVEF and the occurrence of HF events in the elderly population;the unequal coupling interval of PVC is associated with a decrease in LVEF and the occurrence of HF events in the population.Unequal coupling intervals are an independent risk factor.

Ventricular premature beatsHeart failureInfluence

宋红星、张杰、马龙飞、范燕宾

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郑州市第七人民医院心血管内科,郑州 450000

室性早搏 心力衰竭 影响

河南省医学科技攻关计划联合共建项目

LHGJ20220831

2024

医药论坛杂志
中华预防医学会,河南省医学情报研究所

医药论坛杂志

影响因子:0.47
ISSN:1672-3422
年,卷(期):2024.45(11)