Study on effect of esketamine on self-controlled intravenous analgesia and recovery quality after secondary cesarean section
Objective To analyze the effects of esketamine on the efficacy and recovery quality of patient controlled intrave-nous analgesia(PCIA)after secondary cesarean section.Methods A total of 164 puerperae who underwent a second cesarean section under epidural anesthesia in Zhengzhou Jinshui District General Hospital from February 2021 to December 2022 were selected,and the patients were divided into two groups by random number table method:esketamine group and sufentanil group group,with 82 cases in each group.The esketamine group received PCIA with esketamine+tropisetron+ketorolac tromethamine,while the sufentanil group received postoperative sufentanil+tropisetron+ketorolac tromethamine,alcohol for PCIA.The incision visual analog pain score and Ramasy sedation score at 2,6,12,24,and 48 hours after operation,the early postoperative recovery,the number of effective PCIA compressions and the rescue analgesia rate within 48 hours after op-eration were compared between the two groups.The occurrence of adverse reactions during treatment in the two groups was ob-served and recorded.Results At 2,6,12,24,and 48 hours after operation,the incision VAS score and Ramasy sedation score in the two groups increased first and then decreased(P＜0.05),and there were differences in the incision VAS score and Ramasy sedation score between the two groups at different time points,but no statistical significance(P＞0.05).The scores of emotional state,psychological support,self-care ability,physical comfort and total score of the 40-item Quality of Recovery Scale(QoR40)scores in the esketamine group at 24 h and 48 h after operation were higher than those of group sufentanil(P＜0.05).There was no difference significant between the esketamine group and the sufentanil group(17.07％)in the number of effective PCIA compressions and rescue analgesia rate within 48 hours after operation(P＞0.05).The inci-dence of adverse reactions in esketamine group was 40.24％lower than that of Sufentanil group(80.49％)(P＜0.05).Conclusion Bothesketamine and sufentanil can achieve better analgesic and sedative effects in PCIA after secondary cesare-an section,but compared with sufentanil,esketamine can make puerpera better postoperative recovery,and the incidence of nausea,vomiting and pruritus is lower.
Second cesarean sectionPatient controlled intravenous analgesiaEsketamineSufentanil
NETL
NSTL
万方数据
