Value of carboprost tromethamine injection combined with intrauterine balloon during cesarean section of placenta previa
Objective To explore the application effect of carboprost tromethamine injection combined with intrauterine balloon during cesarean section of placenta previa(PP)and its effect on coagulation function and traumatic stress in pu-erperae.Methods The clinical data of 171 puerperaewith PP who underwent cesarean section in the People's Hospital of Anyang from July 2020 to October 2022 were retrospectively analyzed.According to the surgical methods,thepuerpe-rae were divided into observation group(oxytocin+carboprost tromethamine injection+intrauterine balloon,n=89)and control group(oxytocin+carboprost tromethamine injection+B-Lynch suture,n=82).The therapeutic effects were e-valuated by perioperative indicators,bleeding status,postoperative complications,adverse reactions,menstrual recovery time and coagulation function and traumatic stress indicators before and after surgery.Results The blood loss volumes during surgery and at 2 h and 24 h after surgeryinobservation group were less than those in control group the difference was ststistically significant(P＜0.05).The surgical time,hospital stay and duration of bloody lochia in observation group were shorter compared with those in control group the difference was ststistically significant(P＜0.05),but there was no significant difference in the number of cases with hysterectomy between the two groups(P＞0.05).The levels of fibrinogen(FIB)and D-Dimer(D-D)in the two groups at 24 h after surgery were declined compared to before sur-gery the difference was ststistically significant(P＜0.05),and the thrombin time(TT)in both groups was lengthened compared with that before surgery(P＞0.05).The levels of serum E,NE and Cor in the two groups at 24 h after surger-y were significantly enhanced compared with those before surgery,and the levels were higher in control group than those in observation group(P＜0.05).There were 4 cases of adverse reactions in observation group and 5 cases in control group the difference was ststistically significant(P＞0.05).There were no statistical differences in the incidence rates of postoperative complications and menstrual recovery time between both groups(P＞0.05).Conclusion Carboprost tromethamine injection+intrauterine balloon intervention for puerperae with PP can effectively relieve the traumatic stress and reduce the intraoperative and postoperative blood loss volumes,and it has little effect on coagulation function.
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