首页|气流受限程度对慢性阻塞性肺疾病急性加重期后患者肺康复效果的影响

气流受限程度对慢性阻塞性肺疾病急性加重期后患者肺康复效果的影响

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目的 评估气流受限程度(airflow limitation,AL)对急性加重期慢性阻塞性肺疾病(acute exacerbation of chronic obstructive pulmonary disease,AECOPD)患者肺康复(pulmonary rehabilitation,PR)疗效的影响。方法 应用回顾性研究方法,选取2020年7月-2022年4月在南阳市第一人民医院住院治疗的AECOPD患者242例,根据患者AL程度将其分为4组:一级、二级、三级、四级,对比分析4组患者的一般资料及其PR前后的肺功能和血气指标。结果 ①年龄(三级组年龄偏大)、吸烟指数(吸烟量和肺功能分级值成正比例关系,肺功能分级值愈大吸烟量愈多)差异均有统计学意义(P<0。05)。②PR康复后,各组肺功能各项指标均有较明显的好转,高等级程度的AL患者好转的幅度更大,4个组间的各项指标差别趋小,差异无统计学意义(P>0。05)。PaO2、PaCO2等两指标,4个不同程度AL组均有较明显的好转,高等级程度的AL患者好转的幅度更大,4个组间的差别趋小,差异无统计学意义(P>0。05)。③患者AL程度(1、2、3、4级)和PR后的肺功能各项指标的相关性均不显著,和PR后的血气各项指标的相关性也不显著,和上述对应的比较结果互成佐证。结论 AL程度不影响AE-COPD患者PR的疗效。
Effect of airflow restriction on pulmonary rehabilitation after acute exacerbation of chronic obstructive pulmonary disease
Objective To evaluate the effects of airflow limitation(AL)on acute exacerbation of COPD(AECOPD).Effects of pulmonary rehabilitation(PR)in patients with AECOPD.Methods Using the retrospective study method,242 patients with AECOPD hospitalized in Nanyang the First People's Hospital from July 2020 to April 2022 were selected and divided into 4 groups according to their AL degree:first,second,third and fourth.General data and lung function and blood gas indexes before and after PR were compared and analyzed among the 4 groups.Results ① There were statistical-ly significant differences in age(older in the third group)and smoking index(smoking volume was proportional to the lung function grade value,and the larger the lung function grade value,the more smoking volume)(P<0.05).② After PR rehabilitation,the pulmonary function indexes of all groups were significantly improved,and the improvement range of high-grade AL patients was greater,and the difference of various indexes among the 4 groups was smaller,with no statis-tical significance(P>0.05).Two indexes,such as PaO2 and PaCO2,were significantly improved in the 4 AL groups with different degrees,and the improvement range was greater in the high-grade AL patients,and the difference between the 4 groups was smaller,with no statistical significance(P>0.05).③ There was no significant correlation between AL degree(grade 1,2,3,4)and pulmonary function indexes after PR,nor was there significant correlation between AL degree and blood gas indexes after PR,which was mutually supported by the corresponding comparative results above.Conclusion The degree of AL does not affect the efficacy of PR in AECOPD patients.

Chronic obstructive pulmonary diseaseAcute exacerbation periodRestricted airflowPulmonary rehabilitation

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南阳市第一人民医院呼吸危重症医学科,河南南阳 473000

慢性阻塞性肺疾病 急性加重期 气流受限 肺康复

2024

医药论坛杂志
中华预防医学会,河南省医学情报研究所

医药论坛杂志

影响因子:0.47
ISSN:1672-3422
年,卷(期):2024.45(17)
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