Effects of laparoscopic surgery combined with simvastatin and goserelin on and ovarian reserve function
Objective To investigate the effects of simvastatin combined with goserrelin and laparoscopy on ovarian reserve function,endometriosis antibody(EMAb),plasminogen activator inhibitor-1(PAI-1)and monocyte chemotactic pro-tein-1(MCP-1)in endometriosis(EMs).Methods A total of 82 EMs patients diagnosed and treated from April 2020 to May 2022 were selected as the study objects and divided into 2 groups,with 41 patients in each group.Results After treatment,the total effective rate,VE,SOD and 1-year pregnancy rate in observation group were higher than those in control group,while E2,FSH,LH,EMAb,PAI-1,MCP-1,ROS and recurrence rate were lower than those in control group(P＜0.05).Conclusion Simvastatin combined with goserelin and laparoscopic treatment of EMs has a better effect,which is beneficial to improve ovarian function and reduce EMAb,PAI-1,MCP-1 expression.
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