Clincal effects of Shengyu Decoction in treatment of premature ovarian insufficiency
Objective To observe the clincal effects of Shengyu Decoction in the treatment of premature ovarian insuffi-ciency,(P0I).Methods A total of 50 patients with premature ovarian insufficiency who were admitted to the gynecolo-gy outpatient department of RuiJin Hospital Affiliated to Shanghai Jiaotong University School of Medicine were selected from July 1st,2023 to April 30th,2024.All patients were randomly divided into a study group and a control group with 25 patients in each group.For the control group,estrogen and progesterone sequential therapy was used as the treatment method;the study group received Shengyu Decoction treatment.During the treatment process,strictly follow medical ethics and norms,and make a comprehensive evaluation of the efficacy of the two treatment methods.The clinical effica-cy,traditional Chinese medicine(TCM)symptom score,and serum hormone levels of the two groups were carefully compared after treatment.Results Statistical analysis showed that the study group had a total effective rate of treatment as high as 92％,There is a significant difference compared to the control group at 76％(P＜0.05).Before treatment,there was no significant difference in the TCM symptom scores be-tween the two groups,which was not statistically significant(P＞0.05).After treatment,the levels of follicle-stimulating hormone(FSH)and luteinizing hormone(LH)in both groups decreased,while the levels of estradiol(E2)and anti-mullerian hormone(AMH)increased,and these changes were statistically significant(P＜0.05).Further comparison of serum hormone levels before and after treatment between the two groups showed that there was no significant difference in serum follicle-stimulating hormone(FSH),estradiol(E2),luteinizing hormone(LH),and anti-Mullerian hormone(AMH)levels between the two groups before treat-ment,which was not statistically significant(P＞0.05).After treatment,both groups showed a decrease in FSH and LH levels and an increase in E2 and AMH levels.These changes were statistically significant(P＜0.05).However,there was no significant difference between the two groups in terms of hormone levels after treatment(P＞0.05).Con-clusion Shengyu Decoction shows significant therapeutic effect in the treatment of premature ovarian insufficiency(POI),which can effectively alleviate clinical symptoms and regulate hormone levels in patients,thus having high clini-cal application value.
Qi and blood theoryShengyu decoctionPremature ovarian insufficiencyHormone levels
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