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床旁检测血气分析仪与中心实验室检测结果一致性分析

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目的 分析床旁检测(point-of-care testing,POCT)血气分析仪和中心实验室自动化分析仪检测结果的一致性。方法 收集河南省人民医院2024年3月至2024年7月间动脉血气分析标本172份,分别在POCT血气分析仪及中心实验室自动化分析仪检测Hb、HCT、K+、Na+、Cl-、Glu等,计算均值、标准差;计算POCT血气分析仪检测结果与中心实验室检测结果的偏倚及偏倚率;应用ANOVA检验、相关性分析、Passing-Bablok回归分析对POCT血气分析仪与中心实验室检测结果一致性进行分析评价。结果 POCT血气分析仪的Hb、HCT检测结果与中心实验室的偏倚均大于国家卫健委临床检验中心室间质量评价标准;K+、Na+、Cl-、Glu检测结果与中心实验室的偏倚相比均小于国家卫健委临床检验中心室间质量评价标准;POCT台血气分析Hb、HCT与中心实验室自动化分析仪间的结果差异具有统计学意义;K+、Na+、CI-、Glu检测结果与中心实验室检测结果之间比较,差异无统计学意义(P>0。05);POCT血气分析仪Hb、HCT、K+、Na+、Cl-、Glu检测结果与中心实验室模拟回归方程的截距和斜率均在95%置信区间,P>0。05,与中心实验室检测结果具有高度的一致性。结论 POCT血气分析仪与中心实验室Hb、HCT检测结果间的一致性较差;POCT血气分析仪与中心实验室K+、Na+、Cl-、Glu检测结果间均具有较好的一致性。
Comparison of point-of-care blood gas analyzer testing results with central laboratory
Objective To analyze the consistency of the results of point-of-care testing(POCT)blood gas analyzers and blood gas analyzers in central laboratory.Methods Totally 172 arterial blood gas analysis samples anticoagulated by heparin in Henan Province People's Hospital from March 2024 to July 2024 were collected,Hb,HCT,K+,Na+,Cl-,and Glu were tested using both the POCT blood gas analyzer and the automated analyzer in the central laboratory,then calculate the mean and standard deviation.The bias and bias rate between the results of POCT blood gas analyzers and the results of central laboratory were calculated.A NOVA test and Passing-Bablok regression analysis were used to analyze and evaluate the consistency of the results between the POCT blood gas analyzer and the central laboratory.Results The bias between the POCT blood gas analyzer of Hb、HCT and the central laboratory were exceed the external quality assessment standard of National Center for Clinical Laboratories;The bias of K+,Na+,Cl-,and Glu between POCT blood gas analyzer and central laboratory were less than the external quality assessment standard of National Center for Clinical Laboratories.There was no significant difference between the results of blood gas analysis of POCT units and the results of blood gas analysis of central laboratory(P>0.05).The intercept and slope of the test results of POCT blood gas analyzers and the simulated regression equation of the central laboratory were all in the 95%confidence inter-val,P>0.05,which was highly consistent with the test results of the central laboratory.Conclusion The POCT blood gas analyzers have good consistency with the central laboratory on the tests of K+,Na+,Cl-,and Glu.In contrast,the consistency between the POCT blood gas analyzer and the central laboratory for Hb and HCT test results is poor.

Blood gas analyzerPoint-of-care testingConsistencyAutomated analyzer

凌明智、张江峰、胡彪、袁有华、万震

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河南省人民医院检验科,郑州 450003

血气分析仪 床旁检测 一致性 自动化分析

2024

医药论坛杂志
中华预防医学会,河南省医学情报研究所

医药论坛杂志

影响因子:0.47
ISSN:1672-3422
年,卷(期):2024.45(17)