首页|组配式半关节假体治疗儿童膝关节周围恶性骨肿瘤的疗效分析

组配式半关节假体治疗儿童膝关节周围恶性骨肿瘤的疗效分析

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目的 探讨组配式半关节假体治疗儿童膝关节周围恶性骨肿瘤疗效及并发症。方法 回顾性分析2018年1月至2021年12月在阜外华中心血管病医院骨科行保肢手术并获得随访的膝关节周围恶性骨肿瘤患者。所有患者均在术前穿刺活检明确病理诊断,并规范完成术前化疗。根据术前影像学检查确定截骨长度,使用组配式半关节假体联合LARS韧带重建骨缺损及髌韧带、前交叉韧带和侧副韧带。结果 共24例患者均获随访,随访时间30~60个月,平均(41±1。2)个月。24例中骨肉瘤患者19例,尤文肉瘤患者5例,男性15例,女性9例;年龄9~13岁,平均(12。4±0。7)岁,病变位于股骨16例,胫骨8例;截骨长度为13。3 cm,平均(9~21 cm)。3例(12。4%)死亡,2例(8。33%)术后出现了肺部转移,5例(20。83%)出现假体半脱位,在辅助支具固定下不影响正常行走;1例(4。17%)出现术后感染给予清创后愈合。术后3年,使用美国骨骼肌肉系统肿瘤协会评分(mus-culoskeletal tumor society,MSTS)平均(18。3±1。2)分,表明患肢功能良好。结论 对于骨骺尚未闭合的青少年儿童,组配式半关节假体可以保留对侧骨骺,待骨骺闭合后二期手术直接组合成标准肿瘤型膝关节,最大程度降低肢体不等长的并发症。
Analysis of therapeutic effect of combination semi joint prosthesis in treatment of malignant bone tumors around knee joint in adolescents
Objective To explore the efficacy and complications of combination semi joint prostheses in the treatment of malignant bone tumors around the knee joint in adolescents.Methods A retrospective analysis was conducted on 24 patients with malignant bone tumors around the knee joint who underwent limb salvage surgery and received follow-up at the Orthopedics Department of Fuwai Central China Cardiovascular Hospital from January 2018 to December 2021.All patients underwent preoperative biopsy to confirm their pathological diagnosis and completed preoperative chemotherapy in a standardized manner.The length of osteotomy was determined based on preoperative imaging examination.A combi-nation of semi joint prosthesis and LARS ligament was used to reconstruct bone defects,patellar ligament,and lateral collateral ligament.Results Totally 24 patients in this group were followed up for 30-60 months,with an average of(41±1.2)months.There were 19 patients with osteosarcoma,5 patients with Ewing's sarcoma,15 males,and 9 fe-males;the age range was 9-13 years,with an average of(12.4±0.7)years old.The lesions were located in 16 cases of the femur and 8 cases of the tibia.Osteotomy length of 13.3 cm,with an average 9-21 cm.Three cases(12.4%)died,two cases(8.33%)experienced postoperative lung metastasis,and five cases(20.83%)experienced prosthetic subluxation,which did not affect normal walking under the support of assistive braces;one case(4.17%)developed postoperative infection and healed after debridement.After 3 years of surgery,the average(18.3±1.2)score of the A-merican society of skeletal and muscle tumors(MSTS)was used,indicating good limb function.Conclusion For adolescents and children whose epiphyses have not yet closed,the combination of semi joint prostheses can preserve the contralateral epiphyses,and after the epiphyses are closed,they can be directly combined into a standard tumor type knee joint through secondary surgery,minimizing complications of limb inequality.

Malignant bone tumorsSemi joint prosthesisLimb salvage

王振、刘继军、王蕾

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阜外华中心血管病医院骨科,郑州 450000

恶性骨肿瘤 半关节假体 保肢手术

河南省医学科技攻关计划联合共建项目

LHGJ20190775

2024

医药论坛杂志
中华预防医学会,河南省医学情报研究所

医药论坛杂志

影响因子:0.47
ISSN:1672-3422
年,卷(期):2024.45(18)