Extracorporeal membrane oxygenation for lung transplantation of perioperative application
Objective To investigate the effect of extracorporeal membrane oxygenation(ECMO)in the perioperative period of lung transplantation.Methods A retrospective analysis was performed on 63 patients who received lung trans-plantation in the First Affiliated Hospital of Zhengzhou University from January 2017 to December 2022.According to different ECMO catheterization methods,the patients were divided into two groups,including 23 cases in group V-V and 40 cases in group V-A.According to the postoperative ECMO support time,the patients were divided into extend-ed group(ECMO support time＞72 h,7 cases)and non-extended group(ECMO support time≤72h,37 cases).The basic data and postoperative clinical outcomes of the V-A group and the V-V group were compared,and the prog-nosis of the prolonged group and the non-prolonged group was compared.Results There was no significant difference between V-A group and V-V group in gender,age,lung transplantation mode,perioperative ECMO support time,re-moval situation and primary disease(P＞0.05).There was no significant difference in operation time,reintubation rate,exploration hemostasis rate,ICU stay time and hospital stay between the V-A group and the V-V group(P＞0.05).The duration of tracheal extubation in V-A group was longer than that in V-V group(P＜0.05).The cumulative survival rates at 30 d,60 d and 90 d in the extended group were 85.71％,71.43％ and 57.14％,respec-tively,while those in the non-extended group were 91.89％,86.49％ and 78.38％,respectively,which were higher than those in the extended group(P＜0.05).Conclusion The use of ECMO in the perioperative period of lung trans-plant recipients has an important role in improving the survival rate of patients.V-V catheterization has less trauma and can shorten the time of tracheal extubation compared with V-A catheterization.Patients with prolonged ECMO support had worse prognosis than those without prolonged ECMO support.
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