Nutritional status of milk protein allergy in infants and young children and analysis of effect of probiotic treatment
Objective To explore the nutritional status of milk protein allergy in infants and young children,and to ana-lyse the therapeutic effect of probiotics.Methods From March 2021 to March 2022 totally 120 infants with milk protein allergy were recruited as observation objects,and their clinical data were collected and analyzed retrospectively.Accord-ing to their feeding methods,they were divided into control group(deeply hydrolyzed protein formula,n=68)and probi-otic group(deeply hydrolyzed protein formula and probiotics,n=52).To investigate the nutritional status of children,and compare the clinical efficacy,growth and development indicators,allergy indicators,inflammatory factors and clini-cal manifestations before and after treatment.Results The incidence of malnutrition in the children in this study was 31.67％.The effective rate of treatment was higher in the probiotic group(P＜0.05);after treatment,the probiotic group had lower levels of serum IL-6,TNF-α,EOS and IgE,and higher height,body mass and BMI values(all P＜0.05).The improvement of clinical manifestations such as vomiting and milk refusal in the probiotic group was sig-nificantly better than that in the control group(all P＜0.05).Conclusion Infants and children with milk protein allergy are at greater risk of malnutrition,and probiotic treatment can effectively improve their clinical manifestations,allergy and growth indicators,and down-regulate the level of inflammatory factors,which is worth promoting.
Infants and young childrenMilk protein allergyNutritional statusProbiotics treatmentEffect analysis
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