Correlation analysis of cerebral venous reflux disorder and prognosis of cerebral infarction treatment
Objective To analyze the correlation between cerebral venous reflux disorder and the prognosis of cerebral infarction(CI).Methods A total of 138 CI patients admitted to our hospital from July 2021 to August 2022 were en-rolled in the study.All patients were treated with local venous sinus thrombolysis.At 3 months of follow-up,the pa-tients were divided into poor prognosis group(67 cases)and good prognosis group(71 cases)according to the modified Rankin scale(mRS)score.The basic data,cerebral venous reflux and prognosis of the two groups were compared.Uni-variate and multivariate regression analysis were used to analyze the influencing factors of prognosis of thrombolytic thera-py,and Spearman correlation analysis was used to analyze the correlation.Results The CVCS grade and vascular reca-nalization rate in the poor prognosis group were lower than those in the good prognosis group,while the age,brain tissue water content,proportion of patients with deep cerebral vein involvement,proportion of patients with hemorrhagic cere-bral infarction and NIHSS score were higher than those in the good prognosis group(P＜0.05).Multivariate regression analysis showed that CVCS grade,NIHSS score and vascular recanalization rate were independent risk factors affecting the prognosis of thrombolytic therapy.There were significant differences in mRS score and vascular recanalization rate between different CVCS grades of cerebral venous collaterals after thrombolytic therapy(P＜0.05).Spearman correlation analysis showed that CVCS grade was positively correlated with vascular recanalization rate after treatment,and negative-ly correlated with mRS score(r=4.683,-0.574,all P＜0.001).Conclusion CVCS grade,NIHSS score and vas-cular recanalization rate are independent risk factors affecting the prognosis of thrombolytic therapy.CVCS classification is helpful to judge the prognosis of CI thrombolytic therapy.The lower the CVCS classification,the lower the vascular re-canalization rate,the higher the mRS score,and the worse the prognosis.
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