Clinical characteristics analysis of incidental gallbladder cancer
Objective To systematically evaluate the clinical diagnostic and therapeutic characteristics of incidental gallbladder cancer discovered during or after cholecystectomy.Methods Data were retrieved from Pubmed,Embase and the Cochrane Library.Sixteen articles were ultimately selected for meta-analysis to investigate the incidence of incidental gallbladder cancer,the distribution of T staging and the proportion of radical surgeries.Results A total of 1 022 cases of incidental gallbladder cancer were included in the analysis.The incidence of incidental gallbladder cancer in cholecystecto-my for preoperative diagnosis of benign gallbladder disease was 0.004(95%CI:0.003-0.004).T2 stage accounted for 0.402(95%CI:0.372-0.433)of incidental gallbladder cancers.T3 stage accounted for0.258(95%CI:0.230-0.285).The proportion of patients undergoing reoperation for curative purposes was 0.411(95%CI:0.303-0.530).The proportion of patients in whom reoperation was not feasible was 0.089(95%CI:0.042-0.180).Conclusion Most incidental gallblad-der cancers were in T2 and T3 stages.Radical cholecystectomy is necessary for gallbladder cancer staged T2 and above.
万方数据
维普
