肿瘤基础与临床2024,Vol.37Issue(4) :385-389.DOI:10.3969/j.issn.1673-5412.2024.04.004

全流程质量管理在医院静脉用药调配中心抗肿瘤药物调配中的应用

Application of whole-process quality management in the antineoplastic drug dispen-sing in hospital pharmacy intravenous admixture services

刘胜利 周晓燕 王靖 钞艳惠 卢晓静
肿瘤基础与临床2024,Vol.37Issue(4) :385-389.DOI:10.3969/j.issn.1673-5412.2024.04.004

全流程质量管理在医院静脉用药调配中心抗肿瘤药物调配中的应用

Application of whole-process quality management in the antineoplastic drug dispen-sing in hospital pharmacy intravenous admixture services

刘胜利 1周晓燕 1王靖 1钞艳惠 1卢晓静1
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作者信息

  • 1. 郑州大学第一附属医院药学部,河南 郑州 450052
  • 折叠

摘要

目的 探讨全流程质量管理在医院静脉用药调配中心(PIVAS)抗肿瘤药物调配中的应用效果.方法 回顾性分析郑州大学第一附属医院PIVAS抗肿瘤药物差错案例,对抗肿瘤药物调配全流程进行质量控制,通过比较对照组(2022 年1 月至6 月)和实验组(2023 年1 月至6 月)的内部差错率和出门差错率,评价相关管理措施的效果.结果 全流程质量管理措施实施后,抗肿瘤药物内部差错率由 6.74‱下降至 3.67‱(χ2=10.166,P=0.001),抗肿瘤药物出门差错率由1.02‱下降至0.33‱(χ2=4.135,P=0.042).结论 对PIVAS抗肿瘤药物调配实施全流程质量管理,能有效降低抗肿瘤药物差错发生率,在确保成品输液质量和保障患者用药安全上具有重要意义.

Abstract

Objective To explore the application effect of whole-process quality management in the antineoplastic drug dispensing in hospital pharmacy intravenous admixture services(PIVAS).Methods PIVAS antineoplastic drug error cases in the First Affiliated Hospital of Zhengzhou University were analyzed retrospectively,whole-process quality manage-ment of antineoplastic drug dispensing were implemented,and the effect of relevant management measures were evaluated by comparing the internal error rate and outgoing error rate of the control group(January-June 2022)and the experimental group(January-June 2023).Results After the implementation of whole-process quality management measures,the inter-nal error rate of antineoplastic drugs decreased from 6.74‱ to 3.67‱(χ2=10.166,P=0.001),and the outgoing error rate of antineoplastic drugs decreased from 1.02‱ to 0.33‱(χ2=4.135,P=0.042).Conclusion The implementation of whole-process quality management for PIVAS antineoplastic drug dispensing can effectively reduce the incidence of an-tineoplastic drug errors,which is of great significance in ensuring the quality of finished infusion and guaranteeing the safety of patients'medication.

关键词

全流程质量管理/静脉用药调配中心/抗肿瘤药物/调配

Key words

whole-process quality management/pharmacy intravenous admixture services/antineoplastic drugs/dispensing

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出版年

2024
肿瘤基础与临床
河南省抗癌协会,郑州大学,河南省肿瘤医院,河南省肿瘤研究所

肿瘤基础与临床

影响因子:0.861
ISSN:1673-5412
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