Study on Pharmacological Action of Aqueous Extract from Melaleuca Ahemifolia
Objective: To observe the pharmacological action of aqueous extract from Melaleuca Ahemifolia. Methods: The experiments concluded mice ear-swollen induced by croton oil, double broth dilution method, hot plate test, passive cutaneous anaphylaxis (PCA)in mouse, cavy itch test by histamine phosphate and acute toxicity test to observe the pharmacological action of aqueous extract from Melaleuca Ahemifolia. Results: Aqueous Extract from Melaleuca Ahemifolia can inhibit the mice ear-swollen induced by croton oil, enhance the threshold of pain in mice due to hot stimulation, provide obvious bacteriostatic ac-tion on staphylococcus aureus, staphylococcus epidermidis, bacillus coli and albicans Saccharomyces, reduce the PCA and im-prove cavy itch-threshold by histamine phosphate. The acute toxicity test showed that maximum tolerance of water extract of melaleuca alternifolia was 225.62 g crude drug/kg. Conclusion: Aqueous Extract from Melaleuca Ahemifolia can provide obvious anti-inflammatory, analgesic, antimicrobial, anti-allergic and antipruritic effects, with low toxicity.
Melaleuca AhemifoliaAqueous extractPharmacodynamicsAcute toxicity test
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