Effect of Phyllanthus Urinaria Methanol Extract on Blood Glucose and Symptom in Alloxan Diabetic Mice
Objective:To study the effect of Phyllanthus urinaria methanol extract on blood glucose and symptom in alloxan diabetic mice.Methods:Intravenous injection of alloxan induced diabetic model mice were observed in methanol extract of Phyllanthus urinaria L.on mice blood glucose changes and symptom improvement.Results:Methanol extract of Phyllanthus urinaria L(4.8,0.9 and 0.45 g/kg) have improved the body weight of diabetic mice (P＞0.05);methanol extract of Phyllanthus(1.8 and 0.9 g/kg)can reduce the amount of drinking water,improve the animal model of polydipsia symptom diabetic mouse model (P＜0.05 or P＜0.01),and reduce the symptoms of polyuria;methanol extract of Phyllanthus (1.8 and 0.9 g/kg) can reduce blood glucose in diabetic model mice values (P＜0.05).Conclusion:Phyllanthus urinaria methanol extract shows certain reduction in blood sugar in Alloxan induced diabetes model mice,and can improve the diabetes model of animal weight loss,multi drink,and more urine,as well as other symptoms.
国家科技期刊平台
NSTL
万方数据
维普
