Objective:To optimize the forming process of Shenmei buccal tablets.Methods:Single factor experiment was applied to determine the adjuvant material of prescription.The amount of each adjuvant material was studied by the Design-Expert response surface method with taste and disintegration time as indices.Results:The optimum prescription of Shenmei buccal tablets were Shenmei extract 100 g,lactose 300 g,MCC 100 g,and stevioside 4 g.Conclusion:The preparation technology is reasonable and feasible for the industrial production of Shenmei buccal tablets.
关键词
参梅含片/Design-Expert响应面法/口感/崩解时限
Key words
Shenmei buccal tablets/Design-Expert response surface method/taste/disintegration time
维普
万方数据