Research Progress on Traditional Chinese Medicine Intervention of Apolipoprotein E and Its Signaling Pathway in the Treatment of Coronary Heart Disease
This article reviews the research progress of traditional Chinese medicine intervention on apolipoprotein E(ApoE)and its related signaling pathways in the treatment of coronary heart disease.Apo E is closely related to coronary heart disease.Currently,Western medicine mainly treats coronary heart disease through surgical treatment and drug therapy,but both have significant side effects.Chinese herbal medicines can modulate NF-κB,NLRP3 inflammatory vesicles,eNOS/NO,LXRα-ABCA1-ApoA-I and other signaling pathways in a multi-targeted manner to exert anti-inflammatory,modulating lipid metabolism,stabilizing plaque,reducing vascular endothelial dysfunction,and regulating cholesterol reversal transport to treat coronary heart disease.
coronary heart diseaseApo Esignaling pathwaytraditional Chinese medicinereview
万方数据
维普
