首页|甘草中三萜皂苷类成分抗肿瘤及联合抗肿瘤机制研究进展

甘草中三萜皂苷类成分抗肿瘤及联合抗肿瘤机制研究进展

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甘草中三萜皂苷包括甘草酸、甘草次酸、乌拉尔甘草皂苷等,是甘草的主要活性成分之一。近年来,甘草三萜皂苷在抗肝癌、乳腺癌、肺癌等肿瘤及联合抗肿瘤方面的研究取得了一定进展。其可通过诱导肿瘤细胞凋亡、自噬、调控信息通路等机制抑制肿瘤细胞的增殖,在肿瘤的治疗上具有药用价值。
Research Progress on Anti-Tumor and Combined Anti-Tumor Mechanism of Triterpenoid Saponins from Gancao(Glycyrrhizae Radix Et Rhizoma)
Triterpenoid saponins in Gancao(Glycyrrhizae Radix Et Rhizoma)include glycyrrhizic acid,glycyrrhetinic acid,Ural licorice saponins,etc.,and are one of the main active ingredients of Gancao(Glycyrrhizae Radix Et Rhizoma).In recent years,triterpenoid saponins from Gancao(Glycyrrhizae Radix Et Rhizoma)have made some progress in the research of anti-tumor,such as breast cancer,lung cancer and other tumors,and combined anti-tumor.It can inhibit the proliferation of tumor cells by inducing apoptosis,autophagy,and regulating information pathways,and has medicinal value in the treatment of tumors.

Gancao(Glycyrrhizae Radix Et Rhizoma)triterpenoid saponinsanti-tumor mechanismcombined anti-tumor

杨必乾、何昱洁、何慧明、邓毅

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广元市中医医院,四川 广元 628000

甘肃中医药大学,甘肃 兰州 730000

甘草 三萜皂苷 抗肿瘤机制 联合抗肿瘤

国家自然科学基金(地区)项目甘肃省科学基金项目

8196072321JR11RA145

2024

中医药导报
湖南省中医药学会 湖南省中医管理局

中医药导报

CSTPCD
影响因子:0.952
ISSN:1672-951X
年,卷(期):2024.30(1)
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