首页|内热针疗法治疗膝骨关节炎的Meta分析

内热针疗法治疗膝骨关节炎的Meta分析

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目的:分析内热针疗法治疗膝骨关节炎(KOA)的临床疗效。方法:检索内热针干预膝骨关节炎的(单独应用或联合其他治疗方法)的临床随机对照试验(RCT),检索时间限制在数据库建立至2022年11月30日,对符合条件的研究实施质量评价。借助Review Manager 5。4。1软件,根据总有效率、疼痛评分、西安大略和麦克马斯特大学骨关节炎指数(WOMAC)评分、Lysholms评分等结局指标进行Meta分析。结果:最终纳入11项研究,均为RCT,共涉及病例951例,治疗组和对照组分别475例、476例。Meta分析结果显示,治疗组总有效率高于对照组[RR=1。19,95%CI(1。13,1。25),P<0。000 01],WOMAC 评分低于对照组[MD=-9。05,95%CI(-9。98,-8。12),P<0。000 01],疼痛评分低于对照组[SMD=-4。18,95%CI(-5。82,-2。54),P<0。000 01],Lysholms评分高于对照组[MD=16。51,95%CI(4。42,28。60),P<0。00001]。结论:内热针无论是单独治疗还是联合其他方法治疗,均对膝骨关节炎患者产生良好疗效。但鉴于本研究的异质性和样本量的限制,未来需要更大的多中心和高质量的RCT来验证内热针治疗膝骨关节炎的疗效。
Meta-Analysis of Internal Heat-Type Acupuncture Therapy for Knee Osteoarthritis
Objective:To analyze the clinical efficacy of internal heat-type acupuncture therapy for knee osteoarthritis(KOA).Methods:Clinical randomized controlled trials(RCTs)of internal heat-type acupuncture inter-vention for knee osteoarthritis(either alone or in combination with other treatment methods)were searched from the establishment of the database until November 30,2022,and the quality of eligible studies was evaluated.With the help of Review Manager 5.4.1,Meta-analysis was performed according to the total effective rate,pain score,Western Ontario and McMaster University Osteoarthritis Index(WOMAC)score,Lysholms score and other outcome indicators.Results:A total of 11 studies were included,all of which were RCTS,involving a total of 951 cases,475 cases in the treatment group and 476 cases in the control group.Meta-analysis showed that the total effective rate of the treatment group was higher than that of the control group(RR=1.19,95%CI[1.13,1.25],P<0.000 01),the WOMAC score was lower than that of the control group(MD=-9.05,95%CI[-9.98,-8.12],P<0.00001),the pain score was lower than that of the control group(SMD=-4.18,95%CI[-5.82,-2.54],P<0.000 01),and the Lysholms score was higher than that of the control group(MD=16.51,95%CI[4.42,28.60],P<0.000 01).Conclusion:Internal heat-tyep acupuncture therapy,whether treated alone or in combination with other methods,had a good therapeutic effect on patients with KOA.However,due to the heterogeneity and sample size limitations of this study,larger multicenter and high-quality RCTs are needed in the future to verify the efficacy of internal heat-type acupuncture for KOA.

knee osteoarthritisinternal heat-type acupunctureMeta-analysisrandomized controlled trial

田富宝、马良辰、陈坤、徐玉娟、连佳伟、陈梦莹、许建峰、林瑞珠

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宁夏医科大学总医院,宁夏 银川 750004

膝骨关节炎 内热针 Meta分析 随机对照试验

2022年宁夏回族自治区科技厅重点研发计划项目中央引导地方科技发展专项

2022BEG031342021YDDF0029

2024

中医药导报
湖南省中医药学会 湖南省中医管理局

中医药导报

CSTPCD
影响因子:0.952
ISSN:1672-951X
年,卷(期):2024.30(1)
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