首页|中医五行音乐、香薰疗法改善阿尔茨海默病脾肾两虚证认知障碍的疗效观察

中医五行音乐、香薰疗法改善阿尔茨海默病脾肾两虚证认知障碍的疗效观察

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目的:探讨中医五行音乐和香薰疗法对阿尔海默病(AD)脾肾两虚证患者记忆力低下、生活自理能力丧失、认知功能障碍、情绪失稳等认知障碍症状的作用。方法:将50例AD脾肾两虚证患者随机分为对照组、混合疗法组各25例。两组使用常规中西医结合治疗和常规护理,混合疗法组在对照组基础上采用中医五行音乐和香薰疗法辅助治疗,治疗12周。比较两组患者治疗前后病理行为评分(BEHAVE-AD)、智力及精神状态评分(MMES)、Cornell痴呆抑郁评分(CSDD)、中医证候积分,并比较两组临床疗效和患者治疗依从性。结果:两组患者治疗后,BEHAVE-AD、CSDD量表评分均较治疗前降低,MMSE量表评分均较治疗前升高,差异均有统计学意义(P<0。05);混合疗法组治疗后BEHAVE-AD、CSDD量表评分均低于对照组,MMSE量表评分高于对照组,差异均有统计学意义(P<0。05)。两组患者治疗后,中医证候积分均较治疗前降低(P<0。05);混合疗法组治疗后中医证候积分低于对照组(P<0。05)。混合疗法组治疗后总有效率为96。0%(24/25),高于对照组的68。0%(17/25),差异有统计学意义(P<0。05)。混合疗法组患者依从性优良率为92。6%(23/25),优于对照组的80。0%(20/25),差异有统计学意义(P<0。05)。结论:中医五行音乐联合香薰疗法能改善AD脾肾两虚证患者精神认知障碍,提升患者记忆力与生活自理能力,提高其生活质量。
Observation on the Efficacy of Traditional Chinese Medicine Five Elements Music and Aromatherapy on Improving Cognitive Impairment in Patients of Alzheimer's Disease with Spleen and Kidney Deficiency Syndrome
Objective:To investigate the clinical efficacy of Chinese medicine five elements music and aromatherapy on improving the symptoms of cognitive impairment such as low memory,loss of self-care ability,cognitive dysfunction and emotional instability in patients with Alzheimer's disease(AD)with spleen and kidney deficiency syndrome.Methods:A total of 50 patients of AD with syndrome of spleen and kidney deficiency were randomly divided into control group and mixed therapy group.Patients were given conventional Chinese and Western medicine and conventional care in two groups.Patients in mixed therapy group were given Chinese medicine five elements music and aromatherapy auxiliary treatment based on control group for 12 weeks.The BEHAVE-AD score,MMSE scale,CSDD and Chinese medicine symptom score were compared between the two groups before and after treatment.The clinical efficacy and compliance were compared between the two groups.Results:The BEHAVE-AD score and CSDD decreased in two groups after treatment,while MMSE scale increased,with significant difference(P<0.05).The mixed therapy group showed lower BEHAVE-AD score and CSDD than control group after treatment,while higher MMSE scale than control group with significant difference(P<0.05).The Chinese medicine symptom score decreased in two groups after treatment(P<0.05),and the mixed therapy group showed lower Chinese medicine symptom score than control group(P<0.05).The total effective rate of the mixed therapy group was 96.0%(24/25),which was higher than the control group's 68.0%(17/25),and the difference was statistically significant(P<0.05).The excellent compliance rate of patients in the mixed therapy group was 92.6%(23/25),which was better than the control group's 80.0%(20/25),and the difference was statis-tically significant(P<0.05).Conclusion:Chinese medicine five elements music and aromatherapy can improve mental cognitive impairment,memory,self-care ability,and quality of life in Alzheimer's disease patients with spleen and kidney deficiency syndrome.

Alzheimer's diseasespleen and kidney deficiency syndromecognitive impairmentfive elements musicaromatherapyclinical study

兰蓝、朱诗林、蒋谷芬、高娟

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湖南中医药大学第二附属医院,湖南 长沙 410005

阿尔茨海默病 脾肾两虚证 认知障碍 五行音乐 香薰 临床研究

湖南省教育厅课题湖南省教育厅课题

21C023020C1410

2024

中医药导报
湖南省中医药学会 湖南省中医管理局

中医药导报

CSTPCD
影响因子:0.952
ISSN:1672-951X
年,卷(期):2024.30(2)
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