Clinical Study of Xitong Patch(息痛贴剂)in the Treatment of Migraine Blood Stasis Syndrome
Objective:To observe the effect of Xitong Patch on migraine patients with blood stasis syndrome.Methods:A total of 135 migraine patients with blood stasis syndrome were randomly assigned to group A(45 patients),group B(45 patients)and group C(45 patients).Group A patients was treated with Xitong Patch combined with Rizatriptan Benzoate,group B was treated with Xitong Patch,and group C was treated with Rizatriptan Benzoate for 3 days.The pain intensity score of patients was evaluated before and after treatment(on the 7th day of treatment).The scores of TCM syndromes were evaluated before treatment and 1,3 and 7 days after treatment,and the efficacy of TCM syndromes was evaluated on the 7th day.Results:A total of 14 patients were lost during the study,including 4 cases in group A,5 cases in group B and 5 cases in group C.Therefore,121 patients were finally included,41 cases in group A,40 cases in group B and 40 cases in group C.The total effective rate of group A[87.80％(36/41)]and group B[82.50％(33/40)]was higher than that of group C[62.50％(25/40)],and the differences were statistically significant(P＜0.05 or P＜0.01).There was no significant difference in the total effective rate between group A and group B(P＞0.05).The pain intensity scores of the three groups after treatment were lower than those before treatment(P＜0.01).After treatment,the pain intensity score of group A was lower than that of group B and group C,and the pain intensity score of group B was lower than that of group C,the differences were statistically significant(P＜0.01).After treatment,the scores of TCM syndromes in the three groups were gradually decreased,and the differences were statistically significant(P＜0.01).On the 1st,3rd and 7th day of treatment,the scores of TCM syndromes in group A were lower than those in group B and group C,and the differences were statistically significant(P＜0.05).Conclusion:Xitong Patch has a good effect in the treatment of migraine with blood stasis syndrome,which can reduce the degree of pain and improve clinical symptoms to a certain extent.
migraineblood stasis syndromeXitong Patchacupoint application therapyRizatriptan Benzoateclinical study
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维普
