Research Progress on the Treatment of Depression with Sini Powder(四逆散)and Its Combination and Associated Prescriptions
Sini Powder originated from the Treatise on Febrile Diseases and was composed of four medicinal herbs,Chaihu(Bupleuri Radix),Zhishi(Aurantii Fructus Immaturus),Shaoyao(Paeoniae Radix),and Gancao(Glycyrrhizae Radix),which were refined into powder and consumed with water.It is mainly used to treat the syndrome of Yang depression and reverse flow.The prescription compatibility rises and falls to promoted the circulation of Qi,while the converging and dispersing of herbs properties were used to promote liver Qi and nourish liver blood.Modern doctors have applied Sini Powder to depression related research based on the basic pathogenesis of Qi stagnation in depression.They have found that Sini Powder's single-flavoured medicines,medicines pairs,and compound formulas not only have significant therapeutic effects on simple depression in pharmacology and clinical practice,but also can alleviate the accompanying depression of other systemic diseases.The Xuefu Zhuyu Tang(血府逐瘀汤),Chaihu Shugan Powder(柴胡疏肝散),and Xiaoyao San(逍遥散)were all modified drugs based on Sini Powder,belonging to the category of modified prescriptions of Sini Powder.They had been clinically proven to have good antidepressant effects.
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维普
