Clinical Study of Scalp Acupuncture combined with rTMS in the Treatment of Cerebral Infarction
Objective:To investigate the effect of scalp acupuncture combined with repetitive transcranial magnetic stimulation(rTMS)on lower limb motor function and serum neuron-specific enolase(NSE),brain-derived neurotrophic factor(BDNF),nerve growth factor(NGF)and homocysteine(Hey)of patients with cerebral infarction.Methods:A total of 60 patients with ischemic stroke hemiplegia were divided into control group and treatment group,with 30 cases in each group.The control group was treated with conventional exercise,and the treat-ment group was treated with scalp acupuncture combined with rTMS.Before and after 4 weeks of treatment,the Modified Barthel Index(MBI)score,Neurological Deficit Scale(NIHSS)score,Holden Functional Walking Scale(FAC)grading,Fugl Meyer Motor Function Scale(FMAS)score,and serum NSE,Hey,BDNF,and NGF levels were observed in two groups of patients.Results:After 4 weeks of treatment,the MBI score,FMAS score,and FAC grading of both groups increased compared to before treatment(P＜0.01),and the NIHSS score decreased compared to before treatment(P＜0.01).Moreover,the MBI score,FMAS score,and FAC grading of the treatment group were higher than those of the control group(P＜0.01),and the NIHSS score was lower than those of the control group(P＜0.01).After 4 weeks of treatment,the serum NSE and Hey levels of both groups of patients decreased compared to before treatment(P＜0.01),and the serum BDNF and NGF levels increased compared to before treatment(P＜0.01).In addition,the serum NSE and Hey levels of the treatment group patients were lower than those of the control group,and the levels of BDNF and NGF were higher in the control group,and the differences were statistically significant(P＜0.01).Conclusion:The combination of scalp acupuncture and rTMS treatment has good clinical efficacy in improving lower limb motor function in patients with cerebral infarction,which may be related to effectively reducing serum NSE and Hey levels and increasing BDNF and NGF levels in patients with cerebral infarction.
cerebral infarctionscalp acupuncturerepetitive transcranial magnetic stimulation(rTMS)lower limb motor functionneuron specific enolase(NSE)homocysteine(Hcy)brain-derived neurotrophic factor(BDNF)nerve growth factor(NGF)
万方数据
维普
