Discussion on the Thoughts of"Cultivating Soil to Prevent Water"in Treating Chronic Kidney Disease from the Perspective of Intestinal Microecological
This article explores the intrinsic relationship between the dysfunction of"spleen"in traditional Chinese medicine and the dysbiosis of the gut microbiota in chronic kidney disease(CKD).It elaborates on the influence of"spleen"on the composition and function of the gut microbiota,as well as the metabolism and immune function of the body,thereby participating in the occurrence and development of CKD.This provided a modern theoretical basis for the treatment of CKD using the"cultivating soil to prevent water"method in traditional Chinese medicine.The term"cultivating soil to prevent water"is an important component of"mediation of the three jiao"theory system for treating kidney disease by CHEN Yiping,one of the founders of integrated traditional Chinese and Western medicine for kidney disease in China.The microbiota composed of gut microbiota has a profound impact on the progress of CKD and the occurrence of related complications in various aspects."Spleen kidney imbalance"is the root cause of chronic kidney disease.The spleen is located in the middle energizer and has the functions of"ascending clearing","promoting circulation",and"defending",which is similar to the composition and function of intestinal microbiota,and its effect on metabolism and immunity function of the body.The composition balance and functional stability of the gut microbiota can be regarded as the normal state of"spleen controlling ascending clearance".CKD patients suffer from spleen and kidney deficiency,where the spleen fails to clear and the soil fails to prevent water.This leads to an imbalance in the gut microbiota,a loss of self stability in the gut microbiota,changes in composition and function,and the occurrence and development of CKD.The"cultivating soil to prevent water"method focuses on strengthening spleen circulation,regulating intestinal flora,and has good clinical efficacy in treating CKD.
chronic kidney diseaseintestinal microecologyintestinal floracultivating soil to prevent waterspleen and kidney disorders