摘要
总结针灸防治阿尔茨海默病的研究现状,以期揭示针灸在预防和治疗阿尔茨海默症中的潜在机制、疗效评估及未来研究方向,为临床工作中针灸治疗阿尔茨海默病提供理论依据和参考.针灸主要通过影响大脑中认知、记忆等脑区,调节大脑中兴奋性氨基酸水平,调节海马中乙酰胆碱酯酶等机制展现出对阿尔茨海默病的治疗作用.对针灸治疗阿尔茨海默病的临床应用研究分析发现,三阴交、神门、天柱可能是核心组合,临床中常选择头部、面部、颈部和下肢的穴位如百会、四神聪、神门、足三里等,亦有研究表明风池、天柱、风府、中脘等腧穴的选择有更高的症状缓解率.
Abstract
This paper summarizes the research status of acupuncture and moxibustion in the prevention and treatment of Alzheimer's disease,in order to reveal the potential mechanism,efficacy evaluation and future research direction of acupuncture and moxibustion in the prevention and treatment of Alzheimer's disease,and provide theoretical basis and reference for acupuncture and moxibustion in the treatment of Alzheimer's disease in clinical work.Acupuncture mainly shows the therapeutic effect on Alzheimer's disease by affecting brain regions such as cognition and memory,regulating the level of excitatory amino acids in the brain,and regulating acetylcholinesterase in the hippocampus.Through the analysis of the clinical application of acupuncture and moxibustion in the treatment of Alzheimer's disease,it is found that Sanyinjiao(SP 6),Shenmen(HT 7)and Tianzhu(BL 10)may be the core combination.In clinical practice,acupoints of head,face,neck and lower limbs are often selected,such as Baihui(DU 20),Sishencong(EX-HN 1),Shenmen(HT 7)and Zusanli(ST 36).Studies have also shown that the selection of acupoints such as Fengchi(GB 20),Tianzhu(BL 10),Fengfu(DU 16)and Zhongwan(RN 12)has a higher rate of symptom relief.
维普
万方数据