Analysis on the Correlation of TCM Syndrome Types with Risk Factors and Glucolipid Metabolism Indexes in Type 2 Diabetes Mellitus Based on the Theory of Tripe-Heat
Objective:To study the distribution pattern of traditional Chinese medicine(TCM)syndrome types in type 2 diabetes mellitus(T2DM),and to explore the correlation of TCM syndrome types with risk factors and glucolipid metabolism indexes based on the theory of tripe-heat.Methods:The clinical data of 410 cases of T2DM were collected by four diagnostic methods of TCM,and then the TCM syndromes were identified.The general information,risk factors and glucolipid metabolism indexes of the patients were collected.The distribution patterni of the TCM syndrome types of T2DM and the correlation of TCM syndrome types with the general information,risk factors and glucolipid metabolism indexes,were analyzed.Results:The distribution of syndrome types was as follows:stasis-heat syndrome[48.78％(200/410)],dampness-heat syndrome[27.80％(114/410)]and dryness-heat syndrome[23.41％(96/410)].The age and disease course were the highest in stasis-heat syndrome(P＜0.05).The levels of body mass index(BMI),waist circumference and hip circumference were the highest in dampness-heat syndrome(P＜0.05).The main risk factors for diabetes involved family history of diabetes,unhealthy diet and lack of exercise,which accounted for approach or more than 50％of the total.Unhealthy diet and lack of exercise contributed most to the incidence of the dampness-heat syndrome(P＜0.05).The levels of fasting C-peptide(FCP),insulin resistance index(HOMA-IR)and triglyceride(TG)were the highest in dampness-heat syndrome(P＜0.05).β cell function index(HOMA-β)was the lowest in stasis-heat syndrome(P＜0.05).Conclusion:The stasis-heat syndrome was the most common based on the theory of tripe-heat.T2DM patients with damp-heat syndrome are mostly associated with unhealthy diet and lack of exercise,and they are accompanied by the clinical problems of overweight,hyperinsulinemia,hypertriglyc-eridemia and insulin resistance.T2DM patients with stasis-heat syndrome are accompanied by insulin deficiency,older age,and longer disease course.
type 2 diabetes mellitustheory of tripe-heatdryness-heat syndromedamp-heat syndromestasis-heat syndromerisk factorsglucolipid metabolismcorrelation
万方数据
