p38 mitogen-activated protein kinase(p38 MAPK)/nuclear factor-κB(NF-κB)signaling pathway activation has been found to be a key factor contributing to the pathogenesis of allergic rhinitis(AR).Some herbal monomers can reduce the secretion of inflammatory cytokines,reduce oxidative stress injury,correct T cell imbalance,and regulate apoptosis by interfering with the p38 MAPK/NF-κB signaling pathway,thereby exerting the therapeutic effect of AR.
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