一起肉牛副流感病毒3型、巴氏杆菌、牛支原体混合感染的诊治
Diagnosis and Treatment of Mixed Infection of Parainfluenza Virus Type 3,Pasteurella and Mycoplasma Bovis in Beef Cattle
杞天龙 1何顺仙 2邓秋慧 1赵文涛 1邓成松 3李文贵 1李金存2
作者信息
- 1. 云南农业大学动物医学院,云南昆明 650201
- 2. 昆明市寻甸县农业农村局,云南昆明 655200
- 3. 德宏州尚善品味农业有限公司,云南德宏 679200
- 折叠
摘要
牛呼吸道综合征往往是多种病原体混合感染引起,致病机制复杂.云南省昆明市某肉牛养殖场部分犊牛出现了以咳嗽、气短、流鼻涕、腹泻等呼吸道症状为主要表现的呼吸道疾病,随后多头相继死亡,剖检主要病变为气管、胃黏膜、小肠出血,肺脏肝变,肝脏出血肿大,心脏出血,心包黏连等;经采病料用常见呼吸道疾病病原(牛病毒性腹泻病毒,牛冠状病毒,牛副流感病毒3型,牛呼吸道合胞体病毒,牛疱疹病毒1型,多杀性巴氏杆菌,溶血性曼氏杆菌,牛支原体)8联PCR检测试剂盒检测,结果为副流感病毒3型、多杀性巴氏杆菌、牛支原体混合感染.经用加米霉素、10％替米考星和20％氟苯尼考等大环内酯类药物治疗,结合加强饲养管理,多数病牛恢复了健康.
Abstract
Bovine respiratory syndrome is often caused by a mixture of multiple pathogens,with a complex pathogenic mechanism.This study report the outbreak of this disease in calves on a beef cattle farm in Kunming City,which was mainly manifested by respiratory symptoms such as cough,shortness of breath,runny nose and di-arrhea,and subsequently died successively.Field investigation and clinical examination showed that it was suspi-cious infection of respiratory pathogens.In order to confirm the specific cause of the disease,nose swabs were col-lected from the infected cattle,and pathological autopsy was performed on the dead cattle.The pathological chan-ges were mainly tracheal,bronchial,gastric mucosa,small intestine hemorrhage,pulmonary liver change,liver hemorrhage and enlargement,cardiac hemorrhage,pericardium adhesion,etc.The tissue samples of died case were collected for laboratory testing.And PCR detection kit for eight common respiratory pathogen(bovine viral di-arrhea virus,bovine coronavirus,bovine parainfluenza virus type 3,bovine respiratory syncytial virus,Bovine her-pesvirus type 1,Pasteurella multocida,Mantella hemolyticus,mycoplasma bovis)were using.Detection results shows the outbreak were caused by mixed infection of parainfluenza virus type 3,Pasteurella multocida and myco-plasma bovis.After treatment with macrolides such as gamamycin,10％temicosin and 20％flufenicol,combined with intensive feeding management,most of sick cattle recovered.
关键词
副流感病毒3型/多杀性巴氏杆菌/牛支原体/混合感染Key words
parainfluenza virus type 3/pasteurella multocida/mycoplasma bovis/mixed infection引用本文复制引用
基金项目
云南省兽医公共卫生国际联合研发中心项目(2023BI60619)
出版年
2024
国家科技期刊平台
NSTL
万方数据