Computer Simulation of Genetic Drift in the in-situ Conservation Population of Weining Cattle under Different Male-female Ratios
Computer simulation was used to investigate the effects on allele frequency and genotype frequency in the in-situ conservation population of Weining cattle with different male-female ratios among 50 generations,assuming that there was no gene mutation and individual immigration between populations throughout the conserva-tion process.Random selection and mating,and non-overlapping were implemented in all generations.The re-sults showed that the larger the ratio of male to female(1∶99,1∶49),the earlier the fixed generation appeared due to random genetic drift between generations,and the earlier the frequency of allele A1 reached to its maximum(A1=1.0000).The earlier the generation with genotype A1 A1,A1 A2,and A2 A2 reached its maximum(1 or 0),the poorer the conservation effect was;The smaller the male to female ratio(1∶4,1∶9,1∶19),the lower the risk of allele A1 being fixed and the frequency of the three genotypes(A1 A1、A1 A2、A2 A2)reached the extreme(1 or 0),and the better the conservation effect was.