摘要
产气荚膜梭菌是一种重要的人兽共患病原菌,常引起各种动物坏死性肠炎、肠毒血症,突发死亡.云南省昆明市某肉牛养殖场犊牛突发呼吸急速、腹痛、步态不稳,腹部臌胀,随后死亡.剖检主要病变为胸腔积液、肺气肿、肠系膜树枝状出血、胃肠内容物糊状且充满大量酸臭气体等,经采集死亡犊牛大肠、小肠及其内容物,采用SN-T 2709-2010 国境口岸产气荚膜梭菌毒素检测方法对其进行毒素检测,结果显示α毒素基因、β毒素基因、肠毒素基因均为阳性,初步判定为产气荚膜梭菌C型.本次病例诊断提示在云南省存在肉牛产气荚膜梭菌C型感染,肉牛养殖场应加强对产气荚膜梭菌疾病的预防.
Abstract
Clostridium perfringens is an important zoonotic pathogen,which often causes necrotizing enteritis,enterotoxemia and sudden death in various animals.Recently calves in a beef cattle farm in Kunming City,Yunnan Province suddenly had symptom include rapid breathing,abdominal pain,unsteady gait,obvious abdominal disten-sion,and then died.The main pathological changes of autopsy were pleural effusion,emphysema,mesenteric den-dritic hemorrhage,gastrointestinal contents paste and filled with a large amount of sour and odorous gases.The large intestine,small intestine and their contents of dead calves were collected,and the toxin was detected by a na-tional industry Standards for Entry Exit Inspection and Quarantine,the Detection of Clostridium per fringens toxins at frontier port(SN-T 2709-2010).The results showed that the alpha toxin gene,beta toxin gene and enterotox-in gene were all positive,and it was determined to be Clostridium perfringens C type.The diagnosis of this case suggests that there is a case of Clostridium perfringens type C infection in beef cattle in Yunnan Province,which provides a certain reference value for the beef cattle breeding industry,and advocates beef cattle farms to strengthen the prevention of Clostridium perfringens disease.
基金项目
德宏州尚善品味农业有限公司李文贵专家基层科研工作站(2023242212)
云南省兽医公共卫生国际联合研发中心(2023BI60619)
国家科技期刊平台
NSTL
万方数据