Progress in Molecular Biology and Omics Studies of Xinjiang Brown Cattle
[Objective]To review and summarize the current status and progress of Xinjiang brown cattle stud-ies in genetics,breeding,product quality,gastrointestinal microbiology and disease by applying molecular biology and omics techniques in the past decade,and to provide reference for the continuous and in-depth research of Xin-jiang brown cattle.[Methods]We searched the National Library of Medicine(NCBI PUBMED)and China Knowl-edge Network(CNKI)databases for the literatures related to the studies of Xinjiang Brown cattle,and collected 28 SCI articles and 22 Chinese articles.A total of 50 articles was analyzed.[Result]The genes for economic traits of Xinjiang Brown cattle studied in molecular biology included 6 genes for growth traits,7 genes for meat quality traits,10 genes for milk production traits and 4 genes for disease resistance traits.Omics(genomics,transcriptom-ics,proteomics,metabolomics,macro-genomics and DNA methylation)studied the genetic evolution of Xinjiang brown cattle,genomic selection breeding,candidate genes for economic traits,microbial composition and function of digestive tract,and molecular mechanisms of resistance to mastitis and respiratory diseases.[Conclusion]The study on Xinjiang Brown cattle has entered the era of omics,but compared with other cattle breeds in China,it started relatively late and has a relatively small number of literature,which provided a large space for reference and research.We should strengthen the joint research with research institutes in mainland provinces,actively partici-pate in large-scale research programs related to bovine omics at home and abroad,utilize big data resources and new algorithms or models therein,deeply explore the genetic potential and economic value of Xinjiang Brown cat-tle,accelerate the transformation of scientific research results,cultivate new strains of Xinjiang Brown cattle,and make due contribution to the revitalization of the seed industry.
Xinjiang Brown cattlePCRgenometranscriptomeproteomemetabolomemetagenomeDNA methylation