The study of the common syndrome elements and identification criteria of stroke-associated severe pneumonia based on Latent Class Analysis
Objective To explore the syndrome elements of stroke-associated severe pneumonia,establish the identification standard of stroke-related severe pneumonia,provide objective basis for accurate clinical syndrome differentiation treatment.Methods 230 patients with stroke-related severe pneumonia hospitalized in the South Intensive Care Unit of the First Teaching Hospital of Tianjin University of Traditional Chinese Medicine(TCM)were collected from January 2017 to December 2021,and the in-formation of four methods of examinations in TCM and some physical signs of 230 patients were extracted from the electronic medical records.Lantern5.0 was used to analyze the data according to occurrence frequency(>10%)of symptoms and signs and the relevant structure model was established.The structure diagram,mutual information curve and latent class probability distribution table of latent variables and explicit variables were analyzed.The results were interpreted using TCM basic theories.The common syndrome elements of stroke-associated severe pneumonia were obtained.Lanten5.0 software was employed to analyze the clinical features of each syndrome elements and the identification criteria with a threshold value were determined.Results A total of 78 relevant clinical manifestations were performed.And 21 latent variables and 46 subtypes were obtained.The disease syndrome elements of stroke-associated severe pneumonia were preliminarily obtained as follows:phlegm syndrome,heat syndrome,wetness syndrome,Qi deficiency syndrome,Yin deficiency syndrome and Yang deficiency syndrome.Through comprehensive cluster analysis,the preliminary identification criteria of stroke-associated severe pneumonia with a threshold were established.Conclusions The latent structure method was used to analyze the symptoms and signs of 230 cases of stroke-associated severe pneumonia,and the common syndrome elements of stroke-associated severe pneumonia were extracted as follows:phlegm syndrome,heat syndrome,wetness syndrome,Qi deficiency syndrome,Yin deficiency syndrome and Yang deficiency syndrome.Through the method of comprehensive cluster analysis,the identification standard of disease syndrome elements of stroke-associated severe pneumonia was preliminarily established to provide objective basis for clinical syndrome differentiation.
stroke-associated severe pneumoniaLatent Class Analysissyndrome elementsidentification criteria
NETL
NSTL
万方数据
维普
