Research progress on chemical constituents and pharmacological effects of flavonoids in Safflower
Safflower(Carthamus tinctorius L.)is a plant of the asteraceae family,and flavonoids are the characteristic and main active components of it.According to the structure type,it can be divided into four categories,including flavonoids,flavonols,dihydroflavonoids and quinochalcones.Modern phar-macological studies have shown that safflower flavonoids have a wide range of pharmacological effects,such as lowering blood viscosity,reducing inflammatory damage to the vascular endothelium,inhibiting the release of inflammatory factors,improving airway remodelling,inhibiting apoptosis of cardiomyocytes,protecting the central nervous system,protecting the liver etc.,which have therapeutic effect on many kinds of multisystemic disease.In this paper,the chemical constituents and pharmacological effects of safflower flavonoids were reviewed by searching domestic and foreign literatures,so as to provide references for further research of safflower.