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红花中的黄酮类化学成分及其药理作用研究进展

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红花为菊科属植物红花Carthamus tinctorius L.的干燥花,黄酮类化学成分是红花特征性和主要的活性成分,依据结构类型主要分为四类,包括黄酮、黄酮醇、二氢黄酮、醌式查耳酮类.现代药理学研究表明,红花黄酮类化学成分药理作用广泛,如降低血液粘度、减轻血管内皮炎症损伤、抑制炎症因子释放、改善气道重塑、抑制心肌细胞凋亡、保护中枢神经、保肝等,对多系统疾病具有治疗作用.本文通过检索国内外文献,对红花黄酮类化学成分及其药理作用的研究进展进行综述,为红花的进一步研究提供参考.
Research progress on chemical constituents and pharmacological effects of flavonoids in Safflower
Safflower(Carthamus tinctorius L.)is a plant of the asteraceae family,and flavonoids are the characteristic and main active components of it.According to the structure type,it can be divided into four categories,including flavonoids,flavonols,dihydroflavonoids and quinochalcones.Modern phar-macological studies have shown that safflower flavonoids have a wide range of pharmacological effects,such as lowering blood viscosity,reducing inflammatory damage to the vascular endothelium,inhibiting the release of inflammatory factors,improving airway remodelling,inhibiting apoptosis of cardiomyocytes,protecting the central nervous system,protecting the liver etc.,which have therapeutic effect on many kinds of multisystemic disease.In this paper,the chemical constituents and pharmacological effects of safflower flavonoids were reviewed by searching domestic and foreign literatures,so as to provide references for further research of safflower.

Safflowerflavonoidspharmacological effectsresearch progressanti-thromboticanti-inflammatory

李阳、焦扬、牛洁

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100078 北京中医药大学东方医院呼吸热病科

100078 北京中医药大学东方医院老年病科

红花 黄酮类化学成分 药理作用 研究进展 抗血栓 抗炎

2024

环球中医药
中华国际医学交流基金会

环球中医药

CSTPCD
影响因子:1.553
ISSN:1674-1749
年,卷(期):2024.17(1)
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