Discussion on academician Dong Jianhua's medication law for chronic gastritis based on date mining
Objective Based on data mining,this study explores the medication rules of academician Dong Jianhua in the treatment of chronic gastritis.Methods The medical records of academician Dong Jianhua during his tenure at Dongzhimen Hospital of Beijing University of Chinese Medicine and his representative published works were collected,and the prescription information of relevant medical records of chronic gastritis was included.Statistical analysis was carried out based on the frequency analysis,association rule analysis and cluster analysis of traditional Chinese medicine inheritance computing platform,and association rule analysis was performed using SPSS Modeler 18.0 software,as well as cluster analysis and factor analysis using SPSS Statistics 26.0 software.Results A total of 192 prescriptions were included in this study,obtaining 12 high-frequency evidence types and 10 high-frequency treatment rules.A total of 183 Chinese herbs were involved,and the core Chinese herbs were dried tangerine peel,nutgrass galingale rhizome,orange fruit,szechwan chinaberry fruit and citron fruit.Common drug effects were regulating qi,tonifying deficiency,clearing heat and resolving phlegm;the medicinal properties were mainly cold and warm,and the medicinal tastes was mainly bitter and spicy;the meridians were mainly spleen,stomach,lung,and liver.The two drugs with the highest support in the association rule analysis were rhizoma corydalis-fructus toosendan,and the three drugs were caramel malt-parched hawthorn fruit-medicated leaven;4 core prescriptions were obtained using cluster analysis,and 8 common factors were extracted using factor analysis.Conclusion In the treatment of chronic gastritis,academician Dong Jianhua adheres to the principle of integration of rationale and method,and correspondence of prescription and medicine,and is characterized by lightness and smoothness in the use of medicine.
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