Research progress on preventing atherosclerosis pharmacological effects of safflower
Atherosclerosis is a chronic disease closely related to cardiovascular and cerebrovascular diseases.Safflower active ingredients inhibit inflammation by inhibiting nuclear transcription factor-κB information pathway activation and modulating phosphoinositide-3 kinase/protein serine threonine kinase information pathway.Safflower active ingredients inhibit vascular smooth muscle cell proliferation by regulating mitogen-activated protein kinase signaling pathway.The active ingredients of safflower can exert anti-AS effects through anti-oxidative stress,inhibition of platelet aggregation,and regulation of blood lipids.
atherosclerosissafflowerchemical compositionmechanism of action