Study on the distribution of syndrome elements of post-stroke depression in the elderly based on factor analysis and cluster analysis
Objective To explore the distribution of syndrome elements of traditional Chinese medicine(TCM)in elderly patients with post-stroke depression.Methods A retrospective analysis was conducted to collect the basic information and TCM symptoms of 222 elderly patients with post-stroke depression.The frequency of 36 symptoms were analyzed,and the distribution of syndrome elements were explored by factor analysis and cluster analysis.Results The frequency statistics of 36 symptom information extracted showed that depressed mood,irritability,fatigue,palpitations and dreams,dry mouth and dry throat were the common clinical manifestations of elderly patients with post-stroke depression.After factor analysis,it was concluded that 12 common factors,the results suggested the main syndrome elements were qi stagnation,phlegm dampness,blood stasis,heat,blood deficiency,yin deficiency,and qi deficiency.The disease sites were concentrated in the liver,spleen,kidney,and heart.Cluster analysis based on 12 common factors showed that,the common syndromes were liver depression and spleen deficiency(38.74％),kidney deficiency and blood stasis(29.73％),phlegm heat and stasis(24.77％),and heart-liver blood deficiency(6.76％).Conclusion Post-stroke depression in the elderly is a disease of both body and spirit,mainly characterized by liver stagnation and spleen deficiency.Therefore,in clinical treatment,we should emphasize the treatment of both body and spirit,pay attention to toning deficiency and reducing excess,regulating qi apparatus,and focus on soothing the liver and strengthening the spleen on the basis of syndrome analysis and treatment.
万方数据
维普
