首页|肠道微生态在大肠癌精准治疗中作用的研究进展

肠道微生态在大肠癌精准治疗中作用的研究进展

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近年来,肠道微生态在疾病中的作用日益得到关注,尤其是在作为肠道微生态载体的结直肠(大肠)中的研究,更是取得了一定进展,肠道微生态在结直肠癌(colorectal cancer,CRC)发生、发展过程中的作用逐步被阐明.越来越多的研究表明肠道微生态在临床已取得一定疗效的CRC相关精准治疗方式如肿瘤免疫疗法、肿瘤化学疗法、肿瘤益生菌干预等方法中发挥关键作用,其机制仍有待进一步探索.本文就CRC中与微生态相关的精准治疗方式及其潜在机制进行简要综述.
Role of intestinal microecology in precision treatment of colorectal cancer
Recently,the role of intestinal microecology in diseases has attracted increasing attention.Some progress has been achieved in the study of the colorectum,which is the carrier of intestinal microecology,and the role of intestinal microecology in colorectal cancer (CRC) formation and progression has been clarified gradually.More and more studies show that intestinal microecology plays a key role in CRC related precision treatments,such as tumor immunotherapy,chemotherapy and probiotic intervention,which have achieved certain curative effects in clinical treatment,although the mechanism still needs further study.This review briefly discusses the intestinal microecology related precision treatments for CRC and their potential mechanisms.

Colorectal cancerIntestinal microecologyPrecision treatment

李豪、张鹏

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南京医科大学第一临床医学院 江苏省南京市210029

同济大学附属第十人民医院普外科 上海市200072

大肠癌 肠道微生态 精准治疗

国家自然科学基金青年项目上海市科委自然科学基金青年项目高等学校博士学科点专项科研基金

8130206613ZR145950020130072120047

2016

世界华人消化杂志
太原消化病研治中心

世界华人消化杂志

影响因子:1.023
ISSN:1009-3079
年,卷(期):2016.24(32)
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