At present,methanol and air are mainly used as raw materials for the production of formaldehyde,which is divided into silver catalyzed and iron-molybdenum catalyzed methods.The silver catalytic product concentration is not high,while the iron-molybdenum method has the advantages of high production capaci-ty and high concentration of formaldehyde.But this method is not highly adopted in China,and there is much room for optimization and improvement.This paper focuses on the Aspen Plus software simulation of the formaldehyde distillation by the iron-molybdenum methanol oxidation process to optimize the process and improve the product extraction and concentration.A recycling process was applied to efficiently utilize the wa-ter in the system and to obtain two streams of formaldehyde product output with 41%and 72%concentra-tion,respectively.In addition,the sensitivity analysis tool in Aspen Plus software was used to analyze and optimize the parameters of the formaldehyde distillation column in terms of theoretical number of plates,feed plate position and reflux ratio,which provide theoretical basis for efficient and clean production of formalde-hyde.