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早期胃癌患者内镜黏膜下剥离术后疲劳预测模型的构建

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目的 探究早期胃癌患者胃内镜黏膜下剥离术后疲劳(POF)的危险因素,建立并验证早期胃癌POF风险预测模型。方法 采用便利抽样法选取2020年10月—2022年12月于我院治疗的232例早期胃癌患者为研究对象,使用一般资料表、中文版多维度疲乏症状量表、阿姆斯特丹术前焦虑与信息需要量表、匹兹堡睡眠质量量表、艾森克人格问卷简式量表收集相关数据,通过单因素分析和二分类logistic回归分析发生术后疲劳的危险因素,并建立列线图预测模型,选取2023年1-6月在我院治疗的72例患者对模型进行验证。结果 经检验,年龄、性别、睡眠障碍、病灶切除面积、气质类型、术后疼痛和胃肠功能紊乱是早期胃癌患者POF发生的独立危险因素,并以此建立早期胃癌患者POF的列线图模型,经验证该模型具有较好的准确度(H-L检验:x2=2。822,P=0。945)和区分度(AUC=0。0。909,95%CI:0。937~0。980,P<0。001),最大约登指数为 0。648,灵敏度为 0。832,特异度为 0。813,截断值0。319,校准曲线为斜率近似于1的直线。结论 该模型预测效果良好,可为医护人员对早期胃癌POF高风险人群筛查提供参考,及时采取预防性措施。
Analyse of influencing factors and predictive model of fatigue after endoscopic submucosal dissection in patients with early gastric cancer
Objective To explore the risk factors of postoperative fatigue(POF)after endoscopic submucosal dis-section(ESD)in patients with early gastric cancer,and to establish and verify the risk prediction model of POF of early gastric cancer.Methods A total of 232 patients with early gastric cancer in our hospital from January 2020 to December 2022 were selected by convenience sampling method.The general information questionnaire,Chinese ver-sion of Multidimensional Fatigue Inventory,Amsterdam Preoperative Anxiety and Information Need Scale,Pitts-burgh Sleep Quality Scale,and Eysenck Personality Questionnaire Short Scale were used to collect relevant data.The influencing factors of postoperative fatigue were analyzed by single factor analysis and binary logistic regression,and the nomogram prediction model was established.The calibration curve was used to verify the prediction effect of the model.Results Age,gender,sleep disorder,area of lesion resection,temperament type,postoperative pain,and gastrointestinal dysfunction were tested as independent risk factors of POF in patients with early gastric cancer,and the nomograph model for POF in patients with early gastric cancer was established based on this model,which was verified to have good accuracy(H-L test:x2=2.822,P=0.945)and discrimination(AUC=0.0909,95%CI was 0.937-0.980,P<0.001),the maximum Youden index was 0.648,the sensitivity was 0.832,the specificity was 0.813,the cut-off value was 0.319,and the calibration curve was a straight line with slope approximately 1.Conclu-sion The model prediction effect is good,which can be used as a reference for medical staff to screen high-risk groups of postoperative fatigue in early gastric cancer and take preventive measures in time.

early gastric cancergastric endoscopic submucosal dissectionpostoperative fatiguerisk factorsprediction modelnursing

苏洁、陈晨、陈露、宋年

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江苏省中医院南京中医药大学附属医院,江苏南京 210029

南京卫生高等职业技术学校,江苏南京 210046

早期胃癌 胃内镜黏膜下剥离术 术后疲劳 危险因素 预测模型 护理

国家中医临床研究基地开放课题江苏省中医院院级创新发展基金江苏省中医院院级创新发展基金南京中医药大学自然科学基金

JD2023SZ08Y2021CX41Y2021CX43XZR2021018

2024

护士进修杂志
贵州省医药卫生学会办公室

护士进修杂志

CSTPCD
影响因子:2.59
ISSN:1002-6975
年,卷(期):2024.39(2)
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