首页|ICU患者中心静脉导管拔除意外综合征风险的列线图预测模型构建与验证

ICU患者中心静脉导管拔除意外综合征风险的列线图预测模型构建与验证

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目的 探讨重症监护室(ICU)患者中心静脉导管(CVC)拔除意外综合征的影响因素,构建风险预测模型,并进行验证。方法 回顾性收集2018年1月—2022年12月在我院ICU接受CVC置管3 016例患者,根据是否发生CVC拔除意外综合征,分为发生组28例和未发生组2 988例。比较2组一般资料,采用logistic回归分析其危险因素,探讨护理预防措施。结果 ICU患者CVC拔除意外综合征发生率为0。93%,年龄≥65岁、置管时间≥7 d、冠心病史、导管相关血流感染、空气栓塞是ICU患者发生CVC拔除意外综合征的危险因素。利用上述5个因素构建列线图模型,并对列线图模型进行内部验证,绘制校准曲线图显示校正曲线与理想曲线拟合良好,Hosmer-Lemeshow拟合优度检验结果显示,x2=7。240,P=0。412,模型拟合优度良好。AUC=0。742,灵敏度为69。08%,特异度为79。32%,预测结果较好,DCA曲线和临床决策曲线均表明具有较好的临床实用性。结论 年龄≥65岁、置管时间≥7 d、冠心病史、导管相关血流感染和空气栓塞是ICU患者发生CVC拔除意外综合征的独立危险因素,基于此建立的列线图模型对于护理工作者早期干预,降低CVC拔除意外综合征的风险具有重要意义。
Construction and validation of a nomogram prediction model for the risk of accidental syndrome after central venous catheter removal in ICU patients
Objective To explore the influencing factors of unexpected syndrome after central venous catheter(CVC)re-moval in intensive care unit(ICU)patients,so as to provide preventive measures to reduce the occurrence of events.Method A total of 3,016 patients who underwent CVC catheterization in ICU of our hospital from January 2018 to December 2022 were retrospectively collected.They were divided into an incidence group of 28 cases and a non incidence group of 2,988 ca-ses based on the occurrence of accidental CVC removal syndrome.Basic information,past history,and catheterization status of patients between two groups were compared,and logistic regression analysis was used to identify risk factors and explore the nursing prevention measures.Results The incidence of unexpected syndrome after CVC removal in ICU was 0.93%.Age≥65 years old,catheterization time≥7 d,history of coronary heart disease,catheter-related bloodstream infection,and air embolism were risk factors for CVC catheterization patients to develop unexpected syndrome after CVC removal.The nomogram model was constructed by using the above 5 predictive factors,which was internally validated by Bootstrap re-peated sampling 1,000 times,and a calibration curve was drawn toshow a good fit between the calibration curve and the ide-al curve.The results of the Hosmer-Lemreshow goodness of fit test showed that x2=7.240,P=0.412,indicating a good fit of the model.AUC=0.742,the sensitivity was 69.08%,the specificity was 79.32%,and the prediction results were good,and the DCA curve and clinical decision curve both indicated good clinical practicality.Conclusion Age≥65years old,catheterization time≥7 d,history of coronary heart disease,catheter-related bloodstream infection,and air embolism are in-dependent risk factors for CVC removal syndrome in ICU patients.The nomogram model based on this is of great signifi-cance for early intervention by nursing staff to reduce the risk of central venous catheter removal syndrome.

intensive care unitcentral venous catheteraccidental removal syndromerisk factorsnomogram

张洁娟、刘光娣、伍林飞、刘逸文

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四川大学华西医院,四川成都 610041

四川大学华西护理学院,四川成都 610041

重症监护室 中心静脉导管 拔除意外综合征 危险因素 列线图

四川省科技厅重点研发项目

2019YFS0292

2024

护士进修杂志
贵州省医药卫生学会办公室

护士进修杂志

CSTPCD
影响因子:2.59
ISSN:1002-6975
年,卷(期):2024.39(2)
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