Objective To explore the status and influencing factors of self-regulating fatigue in senile stroke pa-tients.Methods A total of 357 elderly stroke patients who met the criteria in neurology department of our hospital were selected as research objects by using convenience sampling method.The general data questionnaire,Self-Regu-lated Fatigue Scale(SPF-S),Connor and Davidson Resilience Scale(CD-RISC),and Social Support Rating Scale(SSRS)were used to survey.Results The score of self-regulating fatigue in 357 elderly stroke patients in this study was(53.58士14.07)points,and the score of cognitive control was the highest in the average score of each dimen-sion.Psychosocial resilience and social support were negatively correlated with the scores and dimensions of self-reg-ulating fatigue in elderly stroke patients from-0.613 to-0.732(P<0.01).The results of the multiple regression analysis showed that age,mating status,duration of disease,psychological resilience,and social support were includ-ed in the regression equation,which could explain 58.6%of the total variation(P<0.05).Conclusion The degree of self-regulated fatigue in elderly stroke patients should be improved,and age,mating status,and duration of disease are the influencing factors of self-regulated fatigue.Medical staff can improve the psychological resilience and social support level of elderly stroke patients to reduce their self-regulated fatigue.