A comparative study of the network characteristics of anxiety and depression symptoms between HIV patients co-infected with tuberculosis and sole HIV infection patients
Objective To explore the network characteristics of anxiety and depression symptoms in patients with human immunodeficiency virus(HIV)/tuberculosis(TB)co-infection and those with only HIV infection.Methods A cross-sectional survey was conducted on inpatients at the Third Peoples Hospital of Shenzhen with HIV complicated by tuberculosis and those with only HIV infection from January 2018 to June 2023.The general patient information,disease-related data,and anxiety and depression scores as determined by the Hospital Anxiety and Depression Scale(HADS)were collected and participants were divided into HIV/TB co-infection and sole HIV infection groups in the network analysis after matching preference scores.The qgraph package was used for network visualization,with the Fruchterman-Reingold algorithm employed for generating network layouts.The differences in the network character-istics of anxiety and depression symptoms between 2 groups were compared.Results After propensity score matc-hing,a total of 520 patient data were included in the network analysis,with 260 patients in each group.It was found that there was no significant difference in anxiety symptoms between patients with HIV/TB co-infection and those with only HIV infection,however,the total depression score was notably higher in the co-infection group(P＜0.05).The network differentiation test was used to assess the network characteristics of anxiety and depression symptoms in both groups,and there was no statistically significant difference between 2 groups(P=0.86).Conclusion Anxiety symptoms in patients with HIV/TB co-infection group are similar to those in patients with sole HIV infection,however,the severity of depression symptoms is higher in the co-infection group.The network char-acteristics of anxiety and depression symptoms are similar between the two groups.
human immunodeficiency virustuberculosisHIV combined with tuberculosisanxietyde-pressionsymptom network
万方数据
维普
